2-甲基-4-苯基-3-丁炔-2-醇合成路线 （共 97 条）
反应条件
triethylamine; tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide T=100°C; Sonogashira reaction; 6 h;
参考文献
Heterocycles, , vol. 66, # 1 p. 621 - 625
反应条件
1: lithium phenylacetylide With 1,4-diiodobutane T=25°C; Alkylation; 20 h; 2: acetone T=25°C; Alkylation; Further stages.;
参考文献
Jones, Graham B.; Wright, Justin M.; Plourde, Gary W.; Hynd, George; Huber, Robert S.; Mathews, Jude E.
Journal of the American Chemical Society, 2000 , vol. 122, # 9 p. 1937 - 1944
反应条件
T=25°C; Alkylation; 20 h;
参考文献
Journal of the American Chemical Society, , vol. 122, # 9 p. 1937 - 1944
反应条件
potassium carbonate in water copper-free Sonogashira coupling; 12 h; Reflux;
参考文献
Khalafi-Nezhad, Ali; Panahi, Farhad
Green Chemistry, 2011 , vol. 13, # 9 p. 2408 - 2415
反应条件
magnesium in tetrahydrofuran; methoxybenzene T=40 - 45°C; 4 h;
参考文献
Russian Journal of Organic Chemistry, , vol. 37, # 1 p. 5 - 8
参考文献
Journal of Organometallic Chemistry, , vol. 168, p. 1 - 11
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, , vol. 34, p. 101
Bulletin de la Societe Chimique de France, , vol. <3> 28, p. 923
反应条件
1: 85 percent / benzene / 2 h / Ambient temperature 2: 77 percent / 1 h / 210 °C / 0.01 Torr 3: 1.) n-BuLi / 1.) hexane, THF, -78 deg C to room temp., 2.) 3 h, room temp. View Scheme
参考文献
Synthesis, , # 3 p. 240 - 243
反应条件
oxygen P=759.8 Torr;
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. 326, # 1 p. 73 - 80
反应条件
ethylmagnesium bromide in diethyl ether
参考文献
Doklady Chemistry, , vol. 245, p. 125 - 126
Dokl. Akad. Nauk SSSR Ser. Khim., , vol. 245, # 2 p. 380 - 382
反应条件
1: Br2 / diethyl ether / 2 h / -10 °C 2: 70 percent / KOH / H2O; diethyl ether / 180 - 220 °C 3: 1.) MeI, Li / 1.) Et2O, 20 deg C, 1 h; 2.) 20 deg C, 12 h View Scheme
参考文献
Journal of Chemical Research, Miniprint, , # 9 p. 3216 - 3245
