2-甲基-4-苯基-3-丁炔-2-醇合成路线 （共 97 条）
反应条件
copper(l) iodide; diethylamine; triphenylphosphine; palladium diacetate 36 h; Heating;
参考文献
Zou, Haixia; Zhou, Liyan; Li, Yuanzhen; Cui, Yi; Zhong, Hanbing; Pan, Zhengying; Yang, Zhen; Quan, Junmin
Journal of Medicinal Chemistry, 2010 , vol. 53, # 3 p. 994 - 1003
反应条件
1-tert-butyl-4,4,4-tris(dimethylamino)-2,2-bis[tris(dimethylamino)-phosphoranylidenamino]-2Λ54Λ5-catenadi(phosphazene) in hexane; dimethyl sulfoxide T=120°C; 24 h;
参考文献
Imahori, Tatsushi; Hori, Chieko; Kondo, Yoshinori
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 9-10 p. 1090 - 1092
反应条件
copper(l) iodide; triethylamine; triphenylphosphine T=90°C; Sonogashira coupling; 3 h; Inert atmosphere;
参考文献
Lin, Bo-Nan; Huang, Shao-Hsien; Wu, Wei-Yi; Mou, Chung-Yuan; Tsai, Fu-Yu
Molecules, 2010 , vol. 15, # 12 p. 9157 - 9173
反应条件
methylaluminum bis(2,6-di-tert-butylphenoxide) in diethyl ether; toluene T=-78°C; 0.5 h;
参考文献
Maruoka, Keiji; Itoh, Takayuki; Sakurai, Minoru; Nonoshita, Katsumasa; Yamamoto, Hisashi
Journal of the American Chemical Society, 1988 , vol. 110, p. 3588 - 3597
反应条件
copper(l) iodide; N-ethyl-N,N-diisopropylamine; tetrakis(triphenylphosphine) palladium(0) in water T=70°C; Sonogashira reaction; 0.5 h;
参考文献
Bhattacharya, Santanu; Sengupta, Saumitra
Tetrahedron Letters, 2004 , vol. 45, # 47 p. 8733 - 8736
反应条件
in chloroform 2 h; UV-irradiation;
参考文献
Gschneidtner, Tina A.; Moth-Poulsen, Kasper
Tetrahedron Letters, 2013 , vol. 54, # 40 p. 5426 - 5429
反应条件
silver(l) oxide; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran T=60°C; 6 h;
参考文献
Ahmed, Mohamed S. Mohamed; Sekiguchi, Akitoshi; Shimada, Tomohiro; Kawashima, Jun; Mori, Atsunori
Bulletin of the Chemical Society of Japan, 2005 , vol. 78, # 2 p. 327 - 330
反应条件
copper(l) iodide; sodium hydrogencarbonate in ethylene glycol dimethyl ether; water T=20°C; 0.5 h;
参考文献
Kang, Suk-Ku; Yoon, Seok-Keun; Kim, Young-Mook
Organic Letters, 2001 , vol. 3, # 17 p. 2697 - 2699
反应条件
potassium carbonate; tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide T=100°C; 6 h;
参考文献
Heterocycles, , vol. 66, # 1 p. 621 - 625
反应条件
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran; N,N-dimethyl-formamide T=20°C; Alkylation; cross-coupling;
参考文献
Tetrahedron Letters, , vol. 41, # 4 p. 437 - 440
