甲基4’-对甲苯磺酰基麦考酚酯合成路线 （共 4 条）
反应条件
triethylamine in dichloromethane T=20°C; 4 h;
参考文献
Ubukata, Makoto; Takamori, Hitomi; Ohashi, Misaki; Mitsuhashi, Shinya; Yamashita, Kaoru; Asada, Tomohisa; Nakajima, Noriyuki; Matsuura, Nobuyasu; Tsuruga, Mie; Taki, Keiko; Magae, Junji
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 17 p. 4767 - 4770
反应条件
1: 78 percent / p-toluenesulfonic acid / 9 h / 20 °C 2: 96 percent / Et3N / CH2Cl2 / 4 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 17 p. 4767 - 4770
反应条件
pyridine; 2,3,5-trimethyl-pyridine; lithium iodide T=150°C; 15 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 17 p. 4767 - 4770
反应条件
2,3,5-trimethyl-pyridine; lithium iodide T=70°C; 17 h;
参考文献
Syntex (U.S.A.) Inc.
Patent: US5525602 A1, 1996 ;
