potassium hydroxide; hydrazine hydrate in diethylene glycol Heating;

1: 10 percent / diisopropylamine / hexamethylphosphoric acid triamide; tetrahydrofuran / 1.) -78 deg C, 45 min; 2.) rt, 3 h 2: triethylamine / Pd(OAc)2,PPh3 / acetonitrile / 48 h / 80 °C View Scheme