N-苄基-N-(3-丁烯)胺合成路线 （共 24 条）
反应条件
sodium iodide in ethanol T=75°C; 4 h;
参考文献
Mccann,S.F.; Overman,L.E.
Journal of the American Chemical Society, 1987 , vol. 109, p. 6107
反应条件
sodium tetrahydroborate; ethanol T=0 - 20°C; 3.66667 h;
参考文献
BRISTOL-MYERS SQUIBB COMPANY; SUN, Chongqing; EWING, William R.; BOLTON, Scott A.; GU, Zhengxiang; HUANG, Yanting; MURUGESAN, Natesan; ZHU, Yeheng
Patent: WO2012/125622 A1, 2012 ;
Location in patent: Page/Page column 115 ;
WO 2012/125622 A1
反应条件
in ethanol T=110°C; 20 h; Inert atmosphere;
参考文献
Dobbs, Adrian P.; Guesne, Sebastien J. J.; Parker, Robert J.; Skidmore, John; Stephenson, Richard A.; Hursthouse, Mike B.
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 5 p. 1064 - 1080
反应条件
lithium aluminium tetrahydride; aluminium trichloride in diethyl ether T=0 - 50°C;
参考文献
Diaz, David D.; Ramirez, Miguel A.; Martin, Victor S.
Chemistry - A European Journal, 2006 , vol. 12, # 9 p. 2593 - 2606
反应条件
triethylamine in dichloromethane 168 h; Heating;
参考文献
Teng, Tsung-Fan; Lin, Jyh-Hwa; Yang, Teng-Kuei
Heterocycles, 1990 , vol. 31, # 7 p. 1201 - 1204
反应条件
potassium carbonate T=70°C;
参考文献
Davies, Stephen G.; Mortimer, Duncan A. B.; Mulvaney, Andrew W.; Russell, Angela J.; Skarphedinsson, Hjalmar; Smith, Andrew D.; Vickers, Richard J.
Organic and Biomolecular Chemistry, 2008 , vol. 6, # 9 p. 1625 - 1634
反应条件
in tetrahydrofuran 0.75 h; Ambient temperature;
参考文献
Wang, Junquan; Zhou, Jianqin; Zhang, Yongmin
Synthetic Communications, 1996 , vol. 26, # 18 p. 3395 - 3399
反应条件
1: T=20°C; 2: With sodium hydroxide in diethyl ether
参考文献
Hess, Wilfried; Burton, Jonathan W.
Chemistry - A European Journal, 2010 , vol. 16, # 41 p. 12303 - 12306
反应条件
1: K2CO3 2: NaBH4 View Scheme
参考文献
Chemical Communications, , # 23 p. 2327 - 2328
反应条件
1: methanol / 18 h / 20 °C / Molecular sieve 2: ethanol; sodium tetrahydroborate / 3.67 h / 0 - 20 °C View Scheme
参考文献
WO2012/125622 A1, ;
WO 2012/125622 A1
