2-溴-4-甲氧基苯甲酸甲酯合成路线 （共 8 条）
反应条件
thionyl chloride 14 h; Heating;
参考文献
Wang, Feijun; Zhang, Yong Jian; Wei, Hao; Zhang, Jiaming; Zhang, Wanbin
Tetrahedron Letters, 2007 , vol. 48, # 23 p. 4083 - 4086
Title/Abstract Full Text View citing articles Show Details
Wei, Hao; Zhang, Yong Jian; Wang, Feijun; Zhang, Wanbin
Tetrahedron Asymmetry, 2008 , vol. 19, # 4 p. 482 - 488
反应条件
1: 2-bromo-4-hydroxybenzoic acid methyl ester With potassium carbonate in N,N-dimethyl-formamide T=20°C; 0.333333 h; Inert atmosphere; 2: methyl iodide in N,N-dimethyl-formamide T=0 - 20°C; 2 h; Inert atmosphere;
参考文献
Jung, Kwan-Young; Vanommeslaeghe, Kenno; Lanning, Maryanna E.; Yap, Jeremy L.; Gordon, Caryn; Wilder, Paul T.; Mackerell, Alexander D.; Fletcher, Steven
Organic Letters, 2013 , vol. 15, # 13 p. 3234 - 3237
反应条件
1.1: SnCl2·2H2O / ethyl acetate / 50 °C / |Inert atmosphere 2.1: sulfuric acid / water / 5 h / 90 °C / |Inert atmosphere 2.2: 0 - 20 °C / |Inert atmosphere 2.3: 1 h / 90 °C / |Inert atmosphere 3.1: potassium carbonate / N,N-dimethyl-formamide / 0.33 h / 20 °C / |Inert atmosphere 3.2: 2 h / 0 - 20 °C / |Inert atmosphere View Scheme
参考文献
Organic Letters, , vol. 15, # 13 p. 3234 - 3237
反应条件
1.1: sulfuric acid / water / 5 h / 90 °C / |Inert atmosphere 1.2: 0 - 20 °C / |Inert atmosphere 1.3: 1 h / 90 °C / |Inert atmosphere 2.1: potassium carbonate / N,N-dimethyl-formamide / 0.33 h / 20 °C / |Inert atmosphere 2.2: 2 h / 0 - 20 °C / |Inert atmosphere View Scheme
参考文献
Organic Letters, , vol. 15, # 13 p. 3234 - 3237
反应条件
1.1: thionyl chloride / methanol / 6 h / 0 °C / |Inert atmosphere; |Reflux 2.1: SnCl2·2H2O / ethyl acetate / 50 °C / |Inert atmosphere 3.1: sulfuric acid / water / 5 h / 90 °C / |Inert atmosphere 3.2: 0 - 20 °C / |Inert atmosphere 3.3: 1 h / 90 °C / |Inert atmosphere 4.1: potassium carbonate / N,N-dimethyl-formamide / 0.33 h / 20 °C / |Inert atmosphere 4.2: 2 h / 0 - 20 °C / |Inert atmosphere View Scheme
参考文献
Organic Letters, , vol. 15, # 13 p. 3234 - 3237
反应条件
1: 59 percent / AlCl3 2: Br2; NaOH 3: SOCl2 View Scheme
参考文献
Tetrahedron Letters, , vol. 48, # 24 p. 4179 - 4182
反应条件
1: Br2; NaOH 2: SOCl2 View Scheme
参考文献
Tetrahedron Letters, , vol. 48, # 24 p. 4179 - 4182
反应条件
water; sodium hydroxide in tetrahydrofuran T=20°C;
参考文献
AMAZENTIS SA; RINSCH, Christopher, L.; BLANCO-BOSE, William; SCHNEIDER, Bernard; MOUCHIROUD, Laurent; RYU, Dongryeol; ANDREUX, Penelope; AUWERX, Johan
Patent: WO2014/4902 A2, 2014 ;
Location in patent: Sheet 30 ;
