4-溴-3-甲氧基苯甲酸甲酯合成路线 （共 14 条）
反应条件
potassium carbonate in acetone 3 h; Heating / reflux;
参考文献
WYETH
Patent: US2006/287522 A1, 2006 ;
Location in patent: Page/Page column 24 ;
US 20060287522 A1
反应条件
potassium carbonate in acetone T=20°C; 22 h;
参考文献
WO2004/89874 A1, ;
Page 46 ;
WO 2004/089874 A1
反应条件
N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile in tetrachloromethane 3 h; Heating / reflux;
参考文献
US6350774 B1, ;
Page column 33 ;
US 6350774 B1
反应条件
potassium carbonate in N,N-dimethyl-formamide
参考文献
Burrows, Andrew D.; Frost, Christopher G.; Mahon, Mary F.; Richardson, Christopher
Angewandte Chemie - International Edition, 2008 , vol. 47, # 44 p. 8482 - 8486
反应条件
potassium carbonate in acetone
反应条件
1: sulfuric acid 2: diethyl ether View Scheme
参考文献
Chemische Berichte, , vol. 74, p. 79,94
反应条件
1: Br2 / acetic acid 2: H2SO4 3: K2CO3 View Scheme
参考文献
Indian Journal of Chemistry, , vol. 11, p. 1081 - 1083
参考文献
Chemische Berichte, , vol. 74, p. 79,94
反应条件
1: lithium hydroxide hydrate; water / methanol; tetrahydrofuran / 1 h / 20 °C 2: potassium carbonate; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 18 h / 20 °C View Scheme
参考文献
BAYER PHARMA AKTIENGESELLSCHAFT; SCHULZE, Volker; MAIS, Franz-Josef
Patent: WO2014/9219 A1, 2014 ;
反应条件
hydrogenchloride; lithium hydroxide in tetrahydrofuran; methanol
参考文献
Vergne, Fabrice; Ducrot, Pierre; Andrianjara, Charles; Bernardelli, Patrick; Lorthois, Edwige
Patent: US2003/45557 A1, 2003 ;
