4-氨基-n-苄基苯磺酰胺合成路线 （共 8 条）
反应条件
1: With SnCl2·2H2O in ethyl acetate 2 h; Reflux; 2: With sodium hydrogencarbonate in water; ethyl acetate pH=7 - 8;
参考文献
Bissinger, Elisabeth-Maria; Heinke, Ralf; Spannhoff, Astrid; Eberlin, Adrien; Metzger, Eric; Cura, Vincent; Hassenboehler, Pierre; Cavarelli, Jean; Schuele, Roland; Bedford, Mark T.; Sippl, Wolfgang; Jung, Manfred
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 12 p. 3717 - 3731
反应条件
C23H38IrN3O(2+)*2BF4(1-) in toluene; acetonitrile T=110°C; 16 h; Inert atmosphere;
参考文献
Bartoszewicz, Agnieszka; Marcos, Rocio; Sahoo, Suman; Inge, A. Ken; Zou, Xiaodong; Martin-Matute, Belen
Chemistry - A European Journal, 2012 , vol. 18, # 45 p. 14510 - 14519
反应条件
1: Et3N or N-methylmorpholine / CH2Cl2 / 0 - 20 °C 2: SnCl2*2H2O / ethyl acetate / 2 h / Heating View Scheme
参考文献
Rubzow
Zhurnal Obshchei Khimii, 1940 , vol. 10, p. 831,840
Chem. Zentralbl., 1940 , vol. 111, # II p. 3475
反应条件
1: Et3N or N-methylmorpholine / CH2Cl2 / 0 - 20 °C 2: SnCl2*2H2O / ethyl acetate / 2 h / Heating View Scheme
参考文献
Kettler; Sakowski; Wiesner; Ortmann; Jomaa; Schlitzer, Martin
Pharmazie, 2005 , vol. 60, # 5 p. 323 - 327
反应条件
1.1: 4-methyl-morpholine / dichloromethane / 0 - 20 °C 2.1: SnCl2·2H2O / ethyl acetate / 2 h / Reflux 2.2: pH 7 - 8 View Scheme
参考文献
Bissinger, Elisabeth-Maria; Heinke, Ralf; Spannhoff, Astrid; Eberlin, Adrien; Metzger, Eric; Cura, Vincent; Hassenboehler, Pierre; Cavarelli, Jean; Schuele, Roland; Bedford, Mark T.; Sippl, Wolfgang; Jung, Manfred
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 12 p. 3717 - 3731
参考文献
El-Mariah, Fatma; Nassar, Ekhlass; Hosny, Mona; Deeb, Ali
Phosphorus, Sulfur and Silicon and the Related Elements, 2009 , vol. 184, # 1 p. 92 - 102
反应条件
2: aqueous hydrochloric acid View Scheme
参考文献
Rubzow
Zhurnal Obshchei Khimii, 1940 , vol. 10, p. 831,840
Chem. Zentralbl., 1940 , vol. 111, # II p. 3475
反应条件
solid phase synthesis; Yield given. Multistep reaction;
参考文献
Garcia-Echeverria, Carlos
Tetrahedron Letters, 1997 , vol. 38, # 52 p. 8933 - 8934
