1-环己烯基-苯基-甲酮合成路线 （共 47 条）
参考文献
Zhang, Pang; Li, Lian-chu
Synthetic Communications, 1986 , vol. 16, # 8 p. 957 - 966
反应条件
magnesium in N,N-dimethyl-formamide
T=-5°C;
参考文献
Aaziz, Akima; Oudeyer, Sylvain; Leonel, Eric; Paugam, Jean Paul; Nedelec, Jean-Yves
Synthetic Communications, 2007 , vol. 37, # 7 p. 1147 - 1154
反应条件
1: 86.5 percent / diethyl ether / 3 h / Ambient temperature
2: 71 percent / conc. H2SO4, hydroquinone / CHCl3 / 6 h / Ambient temperature
View Scheme
参考文献
Ohta; Yamashita; Arita; Kajiura; Kawasaki; Noda; Izumi
Chemical and Pharmaceutical Bulletin, 1995 , vol. 43, # 8 p. 1294 - 1301
参考文献
Kosak; Leyland
Journal of Organic Chemistry, 1956 , vol. 21, p. 733
反应条件
sodium hydride in tetrahydrofuran
1 h; Heating; Yield given;
参考文献
Gerstner, Erwin; Kemmer, Ralf; Christl, Manfred
Chemische Berichte, 1994 , vol. 127, # 2 p. 381 - 392
反应条件
T=210 - 230°C; P=18 - 20 Torr; 1.5 h;
参考文献
Yandovskii; Tselinskii
Russian Journal of Organic Chemistry, 1997 , vol. 33, # 2 p. 147 - 152
反应条件
1.1: n-butyllithium / tetrahydrofuran; hexane / 0 °C / Inert atmosphere
1.2: 0 - 20 °C / Inert atmosphere
1.3: 20 °C / Inert atmosphere
2.1: water; sodium hydroxide / methanol
3.1: bis-triphenylphosphine-palladium(II) chloride; diethylamine; copper(l) chloride / 0 - 20 °C / Inert atmosphere
4.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / -78 °C / Inert atmosphere
4.2: -78 - 20 °C / Inert atmosphere
5.1: indium trifluoromethanesulfonate; butan-1-ol / dichloromethane / 3 h / 20 °C / Inert atmosphere
View Scheme
参考文献
Miura, Katsukiyo; Yamamoto, Kiyomi; Yamanobe, Aya; Ito, Keisuke; Kinoshita, Hidenori; Ichikawa, Junji; Hosomi, Akira
Chemistry Letters, 2010 , vol. 39, # 7 p. 766 - 767
反应条件
1.1: bis-triphenylphosphine-palladium(II) chloride; diethylamine; copper(l) chloride / 0 - 20 °C / Inert atmosphere
2.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / -78 °C / Inert atmosphere
2.2: -78 - 20 °C / Inert atmosphere
3.1: indium trifluoromethanesulfonate; butan-1-ol / dichloromethane / 3 h / 20 °C / Inert atmosphere
View Scheme
参考文献
Miura, Katsukiyo; Yamamoto, Kiyomi; Yamanobe, Aya; Ito, Keisuke; Kinoshita, Hidenori; Ichikawa, Junji; Hosomi, Akira
Chemistry Letters, 2010 , vol. 39, # 7 p. 766 - 767
反应条件
1.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / -78 °C / Inert atmosphere
1.2: -78 - 20 °C / Inert atmosphere
2.1: indium trifluoromethanesulfonate; butan-1-ol / dichloromethane / 3 h / 20 °C / Inert atmosphere
View Scheme
参考文献
Miura, Katsukiyo; Yamamoto, Kiyomi; Yamanobe, Aya; Ito, Keisuke; Kinoshita, Hidenori; Ichikawa, Junji; Hosomi, Akira
Chemistry Letters, 2010 , vol. 39, # 7 p. 766 - 767
反应条件
1.1: Grubb's 2nd generation catalyst / dichloromethane / 12 h / Inert atmosphere; Reflux
2.1: tributylphosphine / tert-butyl alcohol / 3 h / 20 °C / Inert atmosphere
2.2: 20 °C / Inert atmosphere
View Scheme
参考文献
Cran, John W.; Krafft, Marie E.; Seibert, Kimberly A.; Haxell, Thomas F.N.; Wright, James A.; Hirosawa, Chitaru; Abboud, Khalil A.
Tetrahedron, 2011 , vol. 67, # 51 p. 9922 - 9943
