chiral stationary phase including (R)-naphthylethyl-carbamate-functionalized CF6 in methanol; acetic acid; triethylamine; acetonitrile T=20°C; Resolution of racemate; Purification / work up;
1: in tetrahydrofuran T=20°C; 4.91667 h; Resolution of racemate; 2: With isopropanol acetate in methanol T=20°C; 22.25 h; Resolution of racemate; optical yield given as percent ee;
参考文献
Baxter, Carl A.; Cleator, Ed; Brands, Karel M. J.; Edwards, John S.; Reamer, Robert A.; Sheen, Faye J.; Stewart, Gavin W.; Strotman, Neil A.; Wallace, Debra J.
Organic Process Research and Development, 2011 , vol. 15, # 2 p. 367 - 375
