1,3-二(邻甲氧基苯氧基)-2-丙醇合成路线 （共 4 条）
反应条件
1: 2-methoxy-phenol With sodium hydroxide; tetrabutylammomium bromide in water; toluene
T=25 - 30°C; 0.5 h;
2: epichlorohydrin in water; toluene
T=35 - 40°C; 6 h; Product distribution / selectivity;
参考文献
IND-SWIFT LABORATORIES LIMITED
Patent: WO2008/47388 A2, 2008 ;
Location in patent: Page/Page column 12; 14 ;
反应条件
sodium hydroxide in 1,4-dioxane; water; toluene
T=25 - 100°C;
参考文献
Madivada, Lokeswara Rao; Anumala, Raghupathi Reddy; Gilla, Goverdhan; Kagga, Mukkanti; Bandichhor, Rakeshwar
Organic Process Research and Development, 2012 , vol. 16, # 10 p. 1660 - 1664
反应条件
sodium hydroxide in toluene
T=25 - 30°C; SolventConcentration;
参考文献
Madivada, Lokeswara Rao; Anumala, Raghupathi Reddy; Gilla, Goverdhan; Kagga, Mukkanti; Bandichhor, Rakeshwar
Organic Process Research and Development, 2012 , vol. 16, # 10 p. 1660 - 1664
反应条件
sodium acetate; magnesium sulfate; pyridinium chlorochromate in dichloromethane
48 h; Ambient temperature;
参考文献
Hayashita, Takashi; Lee, Joung Hae; Hankins, Matthew G.; Lee, Jong Chan; Kim, Jong Seung; Knobeloch, John M.; Bartsch, Richard A.
Analytical Chemistry, 1992 , vol. 64, # 7 p. 815 - 819
