4-氨基-2,3,5,6-四氟吡啶合成路线 （共 43 条）
反应条件
in dimethyl sulfoxide
Equilibrium constant;
参考文献
Vlasov, V. M.; Terekhova, M. I.; Petrov, E. S.; Shatenshtein, A. I.; Yakobson, G. G.
Journal of Organic Chemistry USSR (English Translation), 1981 , vol. 17, # 10 p. 1807 - 1813
Zhurnal Organicheskoi Khimii, 1981 , vol. 17, # 10 p. 2025 - 2031
反应条件
1: 85 percent / aq. HClO4 / benzene / 0.08 h / Heating
2: Zn; aq. NH3 / 12 h / 20 °C
View Scheme
参考文献
Laev; Evtefeev; Shteingarts
Journal of Fluorine Chemistry, 2001 , vol. 110, # 1 p. 43 - 46
反应条件
1: With trifluoroacetic acid; sodium nitrite
T=0°C; 1 h; Inert atmosphereSchlenk technique;
2: With sodium azide
T=0°C; 1 h; Inert atmosphereSchlenk technique;
参考文献
Jin, Li-Mei; Xu, Xue; Lu, Hongjian; Cui, Xin; Wojtas, Lukasz; Zhang, X. Peter
Angewandte Chemie - International Edition, 2013 , vol. 52, # 20 p. 5309 - 5313
Angew. Chem., 2013 , vol. 125, # 20 p. 5417 - 5421,5
