N-乙酰基-3-吲哚啉酮合成路线 （共 51 条）
反应条件
potassium carbonate T=120°C; 0.5 h;
参考文献
Farmaco, Edizione Scientifica, , vol. 37, # 6 p. 411 - 425
反应条件
1: 96 percent / bromine / CH2Cl2 / 0.33 h / 20 °C 2: 16 percent / dioxane; diethyl ether / 24 h / 20 °C View Scheme
参考文献
Alphonse, France-Aimee; Routier, Sylvain; Coudert, Gerard; Merour, Jean-Yves
Heterocycles, 2001 , vol. 55, # 5 p. 925 - 940
反应条件
sodium hydride 1.) THF, -78 deg C, 30 min, 2.) THF, RT, 18 h; Yield given. Multistep reaction;
参考文献
Merour, J.Y.; Piroelle, S.
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 8 p. 1869 - 1873
反应条件
bromine in dichloromethane T=20°C;
参考文献
Pharmaceutical Chemistry Journal, , vol. 24, # 12 p. 917 - 923
Khimiko-Farmatsevticheskii Zhurnal, , vol. 24, # 12 p. 46 - 51
反应条件
1: 80 percent / piperidine / 5 h / Heating 2: 65 percent / H2 / 10percent Pd/C / ethanol / Ambient temperature 3: 20 percent / NaH / tetrahydrofuran 4: 83 percent / H2, Raney-Ni, NaOH / methanol / Ambient temperature View Scheme
参考文献
Buzas, A.; Merour, J. Y.
Synthesis, 1989 , # 6 p. 458 - 461
反应条件
pyridine; chlorosulfonic acid Behandeln des Reaktionsprodukts mit konz.Kalilauge;
参考文献
Schwenk; Jolles
Biochemische Zeitschrift, 1915 , vol. 69, p. 468
Full Text Show Details
Jolles; Schwenk
Biochemische Zeitschrift, 1915 , vol. 68, p. 348
反应条件
sodium hydroxide in ethanol 2 h; Heating;
参考文献
Katritzky, Alan R.; Li, Qiao-Ling; Fan, Wei-Qiang
Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 1287 - 1292
反应条件
1: 96 percent / bromine / CH2Cl2 / 0.33 h / 20 °C
2: 10 percent / dioxane / 5 h / 20 °C
View Scheme
参考文献
Alphonse, France-Aimee; Routier, Sylvain; Coudert, Gerard; Merour, Jean-Yves
Heterocycles, 2001 , vol. 55, # 5 p. 925 - 940
反应条件
1: 96 percent / bromine / CH2Cl2 / 0.33 h / 20 °C
2: 16 percent / dioxane; diethyl ether / 24 h / 20 °C
3: 99 percent / aq. potassium hydroxide / methanol / 48 h / Heating
View Scheme
参考文献
Alphonse, France-Aimee; Routier, Sylvain; Coudert, Gerard; Merour, Jean-Yves
Heterocycles, 2001 , vol. 55, # 5 p. 925 - 940
反应条件
potassium acetate in acetic acid
24 h; Heating;
参考文献
Sevodin, V. P.; Velezheva, V. S.; Suvorov, N. N.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1981 , vol. 17, # 3 p. 271 - 274
Khimiya Geterotsiklicheskikh Soedinenii, 1981 , vol. 17, # 3 p. 368 - 371
