4-羟基-N-甲基-2-喹啉合成路线 (共 65 条)
反应条件
chromium(VI) oxide in acetic acid
参考文献
Khan, Khalid A.; Shoeb, Aboo
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1985 , vol. 24, p. 62 - 66
反应条件
sodium hydroxide; tetrabutyl-ammonium chloride in toluene T=50°C; 5 h; Further byproducts given;
参考文献
Reisch; Iding
Pharmazie, 1994 , vol. 49, # 1 p. 62 - 62
反应条件
trichlorophosphate in 1,4-dioxane T=120°C; 0.416667 h; microwave irradiation;
参考文献
Hashim, Jamshed; Glasnov, Toma N.; Kremsner, Jennifer M.; Kappe, C. Oliver
Journal of Organic Chemistry, 2006 , vol. 71, # 4 p. 1707 - 1710
反应条件
trichlorophosphate und anschliessend mit Phosphor(V)-chlorid;
参考文献
Lutz et al.
Journal of the American Chemical Society, 1946 , vol. 68, p. 1810
反应条件
thionyl chloride 2 h; Ambient temperature;
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 24, p. 62 - 66
反应条件
1: 82 percent / POCl3 / dioxane / 0.42 h / 120 °C / microwave irradiation 2: NiCl2; Zn; PPh3 / KI / dimethylformamide / 0.42 h / 205 °C / microwave irradiation View Scheme
参考文献
Hashim, Jamshed; Glasnov, Toma N.; Kremsner, Jennifer M.; Kappe, C. Oliver
Journal of Organic Chemistry, 2006 , vol. 71, # 4 p. 1707 - 1710
反应条件
trichlorophosphate und anschliessend mit Phosphor(V)-chlorid;
参考文献
Lutz et al.
Journal of the American Chemical Society, 1946 , vol. 68, p. 1810
反应条件
potassium hydroxide in acetone 14 h; Heating;
参考文献
Reisch, Johannes; Mester, Iuliu
Archiv der Pharmazie (Weinheim, Germany), 1980 , vol. 313, # 9 p. 751 - 755
参考文献
Manandhar, Mangala D.; Hussaini, Falak A.; Kapil, Randhir S.; Shoeb, Aboo
Phytochemistry (Elsevier), 1985 , vol. 24, # 1 p. 199 - 200
反应条件
potassium hydroxide in acetone 14 h; Heating;
参考文献
Reisch, Johannes; Mester, Iuliu
Archiv der Pharmazie (Weinheim, Germany), 1980 , vol. 313, # 9 p. 751 - 755