苯基-2,3,4-三-O-苄基-1-硫代-β-L-岩藻吡喃糖苷合成路线 （共 7 条）
反应条件
chloramine-T in acetonitrile T=20°C; 1 h; Title compound not separated from byproducts;
参考文献
Misra, Anup Kumar; Agnihotri, Geetanjali
Carbohydrate Research, 2004 , vol. 339, # 4 p. 885 - 890
反应条件
tetra-(n-butyl)ammonium iodide; sodium hydride in N,N-dimethyl-formamide
T=20°C; 2 h;
参考文献
Chervin, Stephanie M.; Lowe, John B.; Koreeda, Masato
Journal of Organic Chemistry, 2002 , vol. 67, # 16 p. 5654 - 5662
反应条件
1: With sodium hydroxide in dichloromethane
1.5 h; Reflux;
2: With methanol in dichloromethane
Reflux;
参考文献
GLYCOM A/S; DEKANY, Gyula; AGOSTON, Karoly; BAJZA, Istvan; BOUTET, Julien; BOEJSTRUP, Marie; FANEFJORD, Mette; PEREZ, Ignacio Fegueroa; HEDEROS, Markus; HORVATH, Ferenc; KOVACS-PENZES, Piroska; KROeGER, Lars; OLSSON, Johan; ROeHRIG, Christoph; SCHROVEN, Andreas; VRASIDAS, Ioannis
Patent: WO2010/115934 A1, 2010 ;
Location in patent: Page/Page column 40 ;
反应条件
1: phenyl 2,3,4-tri-O-acetyl-1-thio-L-fucopyranoside With sodium methylate in methanol
0.166667 h; Inert atmosphere;
2: benzyl bromide With Sodium hydride in N,N-dimethyl-formamide; mineral oil
T=20°C; 16 h; Inert atmosphere;
参考文献
Bernardes, Goncalo J. L.; Grayson, Elizabeth J.; Thompson, Sam; Chalker, Justin M.; Errey, James C.; El Oualid, Farid; Claridge, Timothy D. W.; Davis, Benjamin G.
Angewandte Chemie - International Edition, 2008 , vol. 47, # 12 p. 2244 - 2247
反应条件
1: BF3*Et2O
View Scheme
参考文献
Komba, Shiro; Ishida, Hideharu; Kiso, Makoto; Hasegawa, Akira
Carbohydrate Research, 1996 , vol. 285, p. C1-C8
反应条件
1: BF3*Et2O
View Scheme
参考文献
Komba, Shiro; Ishida, Hideharu; Kiso, Makoto; Hasegawa, Akira
Carbohydrate Research, 1996 , vol. 285, p. C1-C8
反应条件
1: pyridine / 29 h / 0 - 20 °C
2: boron trifluoride diethyl etherate / toluene / 18 h / 0 - 20 °C
3: sodium methylate / methanol / 2.5 h / 40 °C
4: sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate / dichloromethane / 1.5 h / |Reflux
View Scheme
参考文献
Glycom A/S Danmarks Tekniske Universitet; Dékany, Gyula; Ágoston, Károly; Bajza, Istvan; Boutet, Julien; Bøjstrup, Marie; Fanefjord, Mette; Pérez Figueroa, Ignacio; Hederos, Markus; Horvath, Ference; Kovács-Pénzes, Piroska; Kröger, Lars; Olsson, Johan; Röhrig, Christoph; Schroven, Andreas; Vrasidas, Ioannis
Patent: US2013/131334 A1, 2013 ;
