N-苄氧羰酰基-L-丝氨酸甲酯合成路线 （共 40 条）
反应条件
phthalimide; triphenylphosphine; diethylazodicarboxylate in benzene 15 h; Ambient temperatureother reagent: 4-nitrobenzoic acid;
参考文献
Journal of Organic Chemistry, , vol. 61, # 7 p. 2544 - 2546
反应条件
1: 2,3,4,6-tetra-O-benzoyl-α-D-glucopyranosyl benzoate With hexamethyl-silane; iodine; zinc(II) iodide in dichloromethane T=20°C; 6 h; 2: (S)-N-(Benzyloxycarbonyl)-serine methyl ester With N-bromosuccinmide in dichloromethane T=5°C; 4 h; Further stages.;
参考文献
Carbohydrate Research, , vol. 343, # 8 p. 1297 - 1308
反应条件
1: H2SO4 2: (saponification) View Scheme
参考文献
Schroeder,E.
Justus Liebigs Annalen der Chemie, 1963 , vol. 670, p. 127 - 136
反应条件
1: 78 percent / DMAP, pyridine / CH2Cl2 / 16 h / -18 °C
2: 98 percent / NaH / dimethylformamide / 1.) 10 min, 2.) 20 deg C, 16 h
View Scheme
参考文献
Knight; Sibley
Tetrahedron Letters, 1993 , vol. 34, # 41 p. 6607 - 6610
反应条件
ammonia in methanol
T=0°C;
参考文献
Ranganathan; Vaish; Shah
Journal of the American Chemical Society, 1994 , vol. 116, # 15 p. 6545 - 6557
反应条件
O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide
参考文献
Panda, Gautam; Rao, N. Venugopal
Synlett, 2004 , # 4 p. 714 - 716
反应条件
1: 78 percent / pyridine, DMAP / CH2Cl2 / 12 h / -20 °C
2: 88 percent / dimethylformamide / 18 h / 20 °C
3: 98 percent / NaBH4 / methanol / 2 h / 20 °C
View Scheme
参考文献
Knight; Sibley
Tetrahedron Letters, 1993 , vol. 34, # 41 p. 6607 - 6610
反应条件
chromium(VI) oxide; acetic acid
参考文献
Stachulski, Andrew V.
Tetrahedron Letters, 1982 , vol. 23, # 37 p. 3789 - 3790
反应条件
1: 27.5 percent / H2SO4 / 1,2-dichloro-ethane / 4 h / Heating
2: 93 percent / Ph3P, CCl4 / dimethylformamide / 4 h / Heating
3: 79 percent / BuLi / tetrahydrofuran; hexane / 1 h / -80 - -65 °C
View Scheme
参考文献
Fuji; Muratake; Natsume
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 9 p. 2344 - 2352
反应条件
1: Py
2: (i) Et2NH, (ii) aq. NaOH, MeOH
View Scheme
参考文献
Photaki,I.
Journal of the American Chemical Society, 1963 , vol. 85, p. 1123 - 1126
