(±)-2-氯-1-苯基乙醇合成路线 (共 94 条)
参考文献
Bulletin de la Societe Chimique de France, , vol. <4> 31, p. 178
反应条件
n-butyllithium; naphthalenyllithium in tetrahydrofuran; diethyl ether -78 deg C, 2 h; to 20 deg C, overnight;
参考文献
Barluenga, Jose; Florez, Josefa; Yus, Miguel
Journal of the Chemical Society, Chemical Communications, 1982 , # 20 p. 1153 - 1154
反应条件
grobacterium radiobacter strain AD1 gene halohydrin dehalogenase mutant in aq. buffer T=30°C; pH=7; 18 h; Enzymatic reaction; stereoselective reaction;
参考文献
Chen, Shao-Yun; Yang, Chen-Xi; Wu, Jian-Ping; Xu, Gang; Yang, Li-Rong
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 16 p. 3179 - 3190
参考文献
Emerson
Journal of the American Chemical Society, 1945 , vol. 67, p. 516
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Reeve; Christoffel
Journal of the American Chemical Society, 1950 , vol. 72, p. 1480,1482
参考文献
Spaeth
Monatshefte fuer Chemie, 1915 , vol. 36, p. 6
参考文献
Spaeth
Monatshefte fuer Chemie, 1915 , vol. 36, p. 6
反应条件
hydrogenchloride Heating;
参考文献
Klosa,J.
Journal fuer Praktische Chemie (Leipzig), 1966 , vol. 33, p. 298 - 306
反应条件
n-butyllithium; oxygen; naphthalenyllithium in tetrahydrofuran; diethyl ether -78 deg C, 3 h;
参考文献
Barluenga, Jose; Florez, Josefa; Yus, Miguel
Journal of the Chemical Society, Chemical Communications, 1982 , # 20 p. 1153 - 1154
反应条件
sodium hydroxide in tetrahydrofuran T=25°C; Title compound not separated from byproducts;
参考文献
Huang, Kun; Wang, Haiyang; Stepanenko, Viatcheslav; De Jesus, Melvin; Torruellas, Carilyn; Correa, Wildeliz; Ortiz-Marciales, Margarita
Journal of Organic Chemistry, 2011 , vol. 76, # 6 p. 1883 - 1886
反应条件
halohydrin dehalogenase from Agrobacterium radiobacter AD1; Tris-SO4 buffer in water T=30°C; Dehydrochlorination; pH=7.5; Title compound not separated from byproducts;
参考文献
Lutje Spelberg, Jeffrey H.; Van Hylckama Vlieg, Johan E. T.; Bosma, Tjibbe; Kellogg, Richard M.; Janssen, Dick B.
Tetrahedron Asymmetry, 1999 , vol. 10, # 15 p. 2863 - 2870