6-甲氧基吲哚-2-羧酸合成路线 （共 19 条）
反应条件
lithium hydroxide in tetrahydrofuran; water
反应条件
sodium hydroxide Heating;
参考文献
Coowar, Djalil; Bouissac, Julien; Hanbali, Mazen; Paschaki, Marie; Mohier, Eliane; Luu, Bang
Journal of Medicinal Chemistry, 2004 , vol. 47, # 25 p. 6270 - 6282
反应条件
1: 94 percent / xylene / Heating 2: 99 percent / aq. NaOH / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 47, # 25 p. 6270 - 6282
反应条件
1: 72 percent / methanol / -10 °C 2: 94 percent / xylene / Heating 3: 99 percent / aq. NaOH / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 47, # 25 p. 6270 - 6282
反应条件
1: lithium hydroxide hydrate / tetrahydrofuran 2: [Rh2(trifluoroacetate)4] / toluene / 0.25 h / 100 °C / |Microwave irradiation View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 6 p. 1740 - 1742
反应条件
n-butyllithium 1.) hexane, THF, -68 deg C, 30 min, 2.) hexane, THF, from -70 deg C to RT; Multistep reaction;
参考文献
Journal of Medicinal Chemistry, , vol. 40, # 13 p. 2003 - 2010
反应条件
ammonia; iron(II) sulfate
参考文献
Journal of the Chemical Society, , vol. 119, p. 1612
Journal of the Chemical Society, , vol. 121, p. 1872
反应条件
1: sodium methylate 2: sodium ethylate / 35 - 40 °C / Zersetzen des Reaktionsprodukts mit Salzsaeure 3: iron (II)-sulfate; ammonia View Scheme
参考文献
Journal of the Chemical Society, , vol. 119, p. 1612
Journal of the Chemical Society, , vol. 121, p. 1872
反应条件
1: sodium ethylate / 35 - 40 °C / Zersetzen des Reaktionsprodukts mit Salzsaeure 2: iron (II)-sulfate; ammonia View Scheme
参考文献
Journal of the Chemical Society, , vol. 119, p. 1612
Journal of the Chemical Society, , vol. 121, p. 1872
反应条件
water; hydrogen bromide; 1-butylpyridinium bromide T=100°C; Microwave irradiationNeat (no solvent);
参考文献
Passiniemi, Mikko; Myllymaeki, Mikko J.; Vuokko, Juha; Koskinen, Ari M.P.
Letters in Organic Chemistry, 2011 , vol. 8, # 1 p. 48 - 52
