1: 1.) Na2HPO4 buffer, 2.) NaBH4 / 1.) DMSO, 5-(carboxymethyl)-2-hydroxymuconate isomerase, RT, 5 min, 2.) DMSO, 30 min 2: H2, (Ph3P)3RhCl / ethanol; benzene / 19 h / 2327.2 Torr / Ambient temperature 3: Pb(OAc)4, AcOH / 2 h / Ambient temperature 4: 13.15 mg / KMnO4, 2M aq. H2SO4 / 1 h View Scheme