2-溴-1-甲基-1H-咪唑合成路线 （共 6 条）
反应条件
1: With n-butyllithium in tetrahydrofuran T=-78°C; 1 h; Inert atmosphere; 2: With carbon tetrabromide in tetrahydrofuran T=-78 - 20°C; 3 h;
参考文献
Oh, Chan Seok; Lee, Chil Won; Lee, Jun Yeob
Chemical Communications, 2013 , vol. 49, # 37 p. 3875 - 3877
反应条件
copper(I) bromide in chloroform; acetonitrile T=20°C; Sandmeyer reaction;
参考文献
Dalton Transactions, , vol. 40, # 43 p. 11382 - 11384
反应条件
N-bromosuccinmide in chloroform 2 h; Heating;
参考文献
Borai, M. El; Moustafa, A. H.; Anwar, M.; Hay, F. I. Abdel
Polish Journal of Chemistry, 1981 , vol. 55, # 7/8 p. 1659 - 1665
反应条件
tetrakis(triphenylphosphine) palladium(0) in toluene 48 h; Heating / reflux;
参考文献
Methylgene, Inc.
Patent: US2007/4675 A1, 2007 ;
Location in patent: Page/Page column 59 ;
US 20070004675 A1
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride
1 h; Heating;
参考文献
McLoughlin, Padraig T.F.; Clyne, Mairead A.; Aldabbagh, Fawaz
Tetrahedron, 2004 , vol. 60, # 37 p. 8065 - 8071
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in tetrahydrofuran; water
Schlenk techniqueRefluxInert atmosphere;
参考文献
Oh, Chan Seok; Lee, Chil Won; Lee, Jun Yeob
Chemical Communications, 2013 , vol. 49, # 37 p. 3875 - 3877
