6,10-二甲基-4,5,9-十一碳三烯-2-酮合成路线 （共 9 条）
反应条件
toluene-4-sulfonic acid; hydroquinone in Petroleum ether
T=80°C; Claisen rearrangement; 16 h;
参考文献
Snowden, Roger L.; Linder, Simon
Helvetica Chimica Acta, 2006 , vol. 89, # 12 p. 3071 - 3086
反应条件
1: 1) n-BuLi / 1) Et2O, hexane, 0 deg C 2) -30 to 0 deg C
2: Na2CO3, benzyltributylammonium chloride / Pd(OAc)2 / dimethylformamide / 16 h / Ambient temperature
3: 1) CuI / 1) Et2O, 0 deg C, 30 min 2) -20 deg C, 1 h
View Scheme
参考文献
Krause, Norbert
Chemische Berichte, 1990 , vol. 123, # 11 p. 2173 - 2180
反应条件
1: Na2CO3, benzyltributylammonium chloride / Pd(OAc)2 / dimethylformamide / 16 h / Ambient temperature
2: 1) CuI / 1) Et2O, 0 deg C, 30 min 2) -20 deg C, 1 h
View Scheme
参考文献
Krause, Norbert
Chemische Berichte, 1990 , vol. 123, # 11 p. 2173 - 2180
反应条件
[Et3NH]+HSO4-
T=95°C; Saucy-Marbet reaction; 24 h;
参考文献
Wang, Congmin; Zhao, Wenjia; Li, Haoran; Guo, Liping
Green Chemistry, 2009 , vol. 11, # 6 p. 843 - 847
反应条件
[Et3NH]+HSO4-
T=95°C; Saucy-Marbet reaction; 24 h;
参考文献
Wang, Congmin; Zhao, Wenjia; Li, Haoran; Guo, Liping
Green Chemistry, 2009 , vol. 11, # 6 p. 843 - 847
参考文献
Hoffmann-La Roche
Patent: US2661368 , 1952 ;
Full Text Show Details
Hoffmann-La Roche
Patent: DE1021354 , 1953 ;
反应条件
potassium hydrogensulfate
3 h; Heating;
参考文献
Zakharova,N.I. et al.
Doklady Chemistry, 1968 , vol. 181, p. 654 - 657
Doklady Akademii Nauk SSSR, 1968 , vol. 181, # 3 p. 603 - 606
反应条件
copper(l) iodide
1) Et2O, 0 deg C, 30 min 2) -20 deg C, 1 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Krause, Norbert
Chemische Berichte, 1990 , vol. 123, # 11 p. 2173 - 2180
反应条件
hydrogen; 5 Pd-CaCO3
T=120 - 220°C; P=112511 Torr; 600 h; Product distribution / selectivity;
参考文献
DSM IP ASSETS B.V.
Patent: WO2006/29737 A1, 2006 ;
Location in patent: Page/Page column 4 ;
