N,N-二甲基羟胺 盐酸盐合成路线 （共 6 条）
反应条件
triethylamine in dichloromethane 22 h; Ambient temperature;
参考文献
Journal of Organic Chemistry, , vol. 53, # 9 p. 1887 - 1894
反应条件
triethylamine in dichloromethane T=10 - 15°C; Inert atmosphere;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 19, # 15 p. 4241 - 4244
反应条件
pyridine; silica gel 1.) CH2Cl2, -70 deg C, 2.) RT; Yield given. Multistep reaction;
参考文献
Banks, Malcolm R.; Hudson, Robert F.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1986 , p. 151 - 156
反应条件
sodium hydrogencarbonate in benzene
参考文献
Konstantinova,N.V. et al.
Zhurnal Organicheskoi Khimii, 1968 , vol. 4, p. 1928 - 1932,1863 - 1867
反应条件
barium dihydroxide; triethylamine T=60°C; 17 h;
参考文献
Sanders; Ames
Tetrahedron Letters, 1985 , vol. 26, # 43 p. 5247 - 5250
反应条件
1: N-methyl-O-methylhydroxyamine hydrochloride With triethylamine in dichloromethane
16 h;
2: 5-bromo-2-chloro-benzoic acid With bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride in dichloromethane
参考文献
JIANGSU HENGRUI MEDICINE CO., LTD.; SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.; Yang, Fanglong; Tang, Peng Cho; Dong, Qing; Tu, Wangyang; Fan, Jiang; Guan, Dongliang; Shen, Guangyuan; Wang, Yang; Yuan, Jijun; Zhang, Limin
Patent: US2013/130997 A1, 2013 ;
Location in patent: Paragraph 0149 ;
