1,6-二(叔-丁氧羰基氨基)己烷合成路线 （共 10 条）
反应条件
manganese; [NiCl2(1,2-dimethoxyethane)]; Ru(4,4′,4''-tri-t-butyl-2,2′;6,2″-terpyridine)Cl3 in N,N-dimethyl-formamide T=40°C; 24 h;
参考文献
Prinsell, Michael R.; Everson, Daniel A.; Weix, Daniel J.
Chemical Communications, 2010 , vol. 46, # 31 p. 5743 - 5745
反应条件
1: hexamethylene diamine With triethylamine T=20°C; 0.5 h; Inert atmosphere; 2: di-tert-butyl dicarbonate T=20°C; 12 h; Inert atmosphere;
参考文献
Sinha, Mantosh K.; Reany, Ofer; Yefet, Maayan; Botoshansky, Mark; Keinan, Ehud
Chemistry - A European Journal, 2012 , vol. 18, # 18 p. 5589 - 5605
反应条件
in 1,4-dioxane 22 h;
参考文献
Suryakiran; Prabhakar; Reddy, T. Srikanth; Rajesh; Venkateswarlu
Tetrahedron Letters, 2006 , vol. 47, # 46 p. 8039 - 8042
反应条件
pyridine; N,N'-dimethyl-N,N'-propyleneurea; 4,4'-dimethoxy-2,2'-bipyridine; NiI2*3.5H2O; sodium iodide; zinc T=20 - 60°C; 20 h; chemoselective reaction;
参考文献
Everson, Daniel A.; Jones, Brittany A.; Weix, Daniel J.
Journal of the American Chemical Society, 2012 , vol. 134, # 14 p. 6146 - 6159
反应条件
copper (II) 2-ethylhexanoate in benzene Heating;
参考文献
Sinyavskii,V.G. et al.
Journal of Organic Chemistry USSR (English Translation), 1967 , vol. 3, # 5 p. 836 - 839
Zhurnal Organicheskoi Khimii, 1967 , vol. 3, # 5 p. 870 - 873
反应条件
in diethyl ether; dimethyl sulfoxide 1 h; Ambient temperature;
参考文献
Hansen, J. B.; Nielsen, M. C.; Ehrbar, U.; Buchardt, O.
Synthesis, 1982 , # 5 p. 404 - 405
反应条件
in diethyl ether; dimethyl sulfoxide 2 h; Ambient temperature;
参考文献
Hansen, John B.; Langvad, Eyvind; Frandsen, Flemming; Buchardt, Ole
Journal of Medicinal Chemistry, 1983 , vol. 26, # 10 p. 1510 - 1514
参考文献
Hansen, John B.; Langvad, Eyvind; Frandsen, Flemming; Buchardt, Ole
Journal of Medicinal Chemistry, 1983 , vol. 26, # 10 p. 1510 - 1514
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 12 h; Reflux;
参考文献
Choi, Doo Li; Jang, Sun Jeong; Cho, Sehyeon; Choi, Hye-Eun; Rim, Hong-Kun; Lee, Kyung-Tae; Lee, Jae Yeol
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 6 p. 1565 - 1570
反应条件
1: lithium aluminium tetrahydride / tetrahydrofuran / 0 °C / |Reflux
2: hydrogenchloride / methanol / 0 - 20 °C
3: lithium aluminium tetrahydride / tetrahydrofuran / 0 °C / |Reflux
View Scheme
参考文献
Choi, Doo Li; Jang, Sun Jeong; Cho, Sehyeon; Choi, Hye-Eun; Rim, Hong-Kun; Lee, Kyung-Tae; Lee, Jae Yeol
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 6 p. 1565 - 1570
