1: N,N-dimethyl-formamide With trichlorophosphate T=25°C; 0.333333 h; 2: 3,5-dimethoxy-benzyl alcohol T=25 - 75°C; 2 h; Further stages.;

trichlorophosphate in N,N-dimethyl-formamide

1.1: 96 percent / BBr3 / CH2Cl2 / 20 h / 25 °C 2.1: 97 percent / imidazole / CH2Cl2; tetrahydrofuran / 12 h / 25 °C 3.1: 100 percent / NaOCl2; sulfamic acid / tetrahydrofuran; H2O; dimethylsulfoxide / 0.5 h / 0 °C 4.1: 75 percent / tri-2-furyl phosphite; DIAD / benzene / 12 h / 25 °C 5.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -20 °C 5.2: n-BuLi / tetrahydrofuran; hexane / 2 h / -78 °C 6.1: 88 percent / imidazole / dimethylformamide / 3 h / 25 °C 7.1: 60 percent / (PCy)3Cl2Ru=CHPh(1,3-di-Mes-imidazolidine-2-yl) / CH2Cl2 / 2 h / 42 °C 8.1: mCPBA / CH2Cl2 / 0.08 h / -10 °C 8.2: Ac2O; Et3N / H2O; tetrahydrofuran / 12 h / 60 °C 9.1: 58 percent / NaHCO3 / methanol; H2O / 24 h 10.1: 58 percent / SO2Cl2 / diethyl ether / 0 °C View Scheme