亚甲基二磷酸四乙酯合成路线

1660-94-2亚甲基二磷酸四乙酯+

150250-33-2四乙基[3-(四氢-2H-吡喃-2-基氧基)-1,1-丙烷二基]二(膦酸酯)

→

150250-34-3四乙基(4-羟基-1,1-丁烷二基)二(膦酸酯)

参考文献

TARGANTA THERAPEUTICS, INC.
Patent: US2010/113333 A1, 2010 ;

1660-94-2亚甲基二磷酸四乙酯

→

136496-88-3

参考文献

Bulman Page, Philip C; Moore, Jonathan P.G; Mansfield, Ian; McKenzie, Michael J; Bowler, Wayne B; Gallagher, James A
Tetrahedron, 2001 , vol. 57, # 9 p. 1837 - 1847

1660-94-2亚甲基二磷酸四乙酯+

122-78-1苯乙醛

→

135760-95-1

参考文献

Kiddle, James J.; Babler, James H.
Journal of Organic Chemistry, 1993 , vol. 58, # 13 p. 3572 - 3574

33821-94-22-(3-溴丙氧基)四氢-2H-吡喃+

1660-94-2亚甲基二磷酸四乙酯

→

150250-33-2四乙基[3-(四氢-2H-吡喃-2-基氧基)-1,1-丙烷二基]二(膦酸酯)

参考文献

Tanaka, Kelly S.E.; Houghton, Tom J.; Kang, Ting; Dietrich, Evelyne; Delorme, Daniel; Ferreira, Sandra S.; Caron, Laurence; Viens, Frederic; Arhin, Francis F.; Sarmiento, Ingrid; Lehoux, Dario; Fadhil, Ibtihal; Laquerre, Karine; Liu, Jing; Ostiguy, Valerie; Poirier, Hugo; Moeck, Gregory; Parr Jr., Thomas R.; Rafai Far, Adel
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 20 p. 9217 - 9229

1984-15-2亚甲基二磷酸+

1660-94-2亚甲基二磷酸四乙酯

→

1499-29-2亚甲基双膦酰二氯

参考文献

Maier,L.
Helvetica Chimica Acta, 1965 , vol. 48, p. 133 - 142

1660-94-2亚甲基二磷酸四乙酯

→

1478-53-1二氟甲基膦酸二乙酯+

78715-56-7四乙基氟代亚甲基二磷酸酯+

78715-58-9四乙基二氟亚甲基二膦酸酯

参考文献

Journal of Organic Chemistry, , vol. 46, # 22 p. 4573 - 4576

1660-94-2亚甲基二磷酸四乙酯+

100-52-7苯甲醛

→

20408-33-7

参考文献

Rambaud, Monique; Vecchio, Anthony del; Villieras, Jean
Synthetic Communications, 1984 , vol. 14, # 9 p. 833 - 842

1660-94-2亚甲基二磷酸四乙酯

→

20408-33-7

参考文献

Costisella, Burkhard; Gross, Hans; Jeroschewski, Paul; Keitel, Iris; Schwarz, Karl-Heinz
Phosphorus and Sulfur and the Related Elements, 1987 , vol. 29, p. 159 - 164

50-00-0甲醛+

1660-94-2亚甲基二磷酸四乙酯

→

37465-31-91,1-双(二乙氧基磷酰基)乙烯

参考文献

Kubicek, Vojtech; Kotek, Jan; Hermann, Petr; Lukes, Ivan
European Journal of Inorganic Chemistry, 2007 , # 2 p. 333 - 344

1660-94-2亚甲基二磷酸四乙酯

→

37465-31-91,1-双(二乙氧基磷酰基)乙烯

参考文献

Nasman; Jan-Anders H.; Hormi; Osmo; Pajunen; Esko O.; Sundell; Mats J.
Patent: US5200554 A1, 1993 ;