反应条件
1: 6-bromo-4,4-dimethyl-3,4-dihydro-2H-1-benzothiopyran With n-butyllithium in tetrahydrofuran T=-78°C; 0.166667 h; 2: N,N-dimethyl-formamide in tetrahydrofuran T=20°C;
参考文献
MERCK SHARP and DOHME CORP.; DUFFY, Joseph, L.; BAO, Jianming; ONDEYKA, Debra, L.; TYAGARAJAN, Sriram; SHAO, Patrick; YE, Feng; KATIPALLY, Revathi; ZWICKER, Aaron; SHERER, Edward, C.; PLOTKIN, Michael A.; MONINGKA, Remond; HUSSIAN, Zahid; WOOD, Harold B.; UJJAINWALLA, Feroze; ROMERO, Anthony; FINKE, Paul; ZANG, Yi; LIU, Weiguo
Patent: WO2012/24183 A1, 2012 ;
Location in patent: Page/Page column 187-188 ;
WO 2012/024183 A1
