3-(二甲氨基)苯甲酸甲酯合成路线 （共 17 条）
反应条件
in hexane; dichloromethane
参考文献
SmithKline Beecham p.l.c.
Patent: US5536745 A1, 1996 ;
参考文献
Griess
Chemische Berichte, 1873 , vol. 6, p. 586
反应条件
hydrogen; sodium methylate; dichloro-bis-[2-(diphenylphosphino)ethylamine]ruthenium in tetrahydrofuran T=100°C; P=37503.8 Torr; 2.5 h; Product distribution / selectivity;
参考文献
SAUDAN, Lionel; Dupau, Philippe; Riedhauser, Jean-Jacques; Wyss, Patrick
Patent: US2008/71121 A1, 2008 ;
Location in patent: Page/Page column 13 ;
反应条件
1: 81 percent / LiAlH4 / diethyl ether / 3 h / Heating 2: 5 percent / pyridinium chlorochromate; pyridine; Na2CO3 / CH2Cl2 / Heating View Scheme
参考文献
Sakurai, Hiromi; Izuoka, Akira; Sugawara, Tadashi
Journal of the American Chemical Society, 2000 , vol. 122, # 40 p. 9723 - 9734
参考文献
Uijttewaal,A.P. et al.
Journal of Organic Chemistry, 1979 , vol. 44, p. 3157 - 3168
反应条件
tellurium; Bi(NO3)3·5H2O; 5 palladium on charcoal; oxygen in methanol
T=60°C; P=760.051 Torr; 8 h;
参考文献
Powell, Adam B.; Stahl, Shannon S.
Organic Letters, 2013 , vol. 15, # 19 p. 5072 - 5075
反应条件
in methanol; diethyl ether; dichloromethane
T=0°C; 2.33333 h;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2009/32667 A1, 2009 ;
Location in patent: Page/Page column 163 ;
WO 2009/032667 A1
反应条件
sulfuric acid
T=80°C; 40 h;
参考文献
Wang, Pengfei; Zhou, Lei; Zhang, Xin; Liang, Xing
Chemical Communications, 2010 , vol. 46, # 9 p. 1514 - 1516
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=20°C; 10 h; Inert atmosphereSealed tube;
参考文献
Zou, Liang-Hua; Reball, Jens; Mottweiler, Jakob; Bolm, Carsten
Chemical Communications (Cambridge, United Kingdom), 2012 , vol. 48, # 92 p. 11307 - 11309,3
参考文献
Price; Belanger
Journal of the American Chemical Society, 1954 , vol. 76, p. 2682
