1,2,3,4-四氢-9H-吡啶[3,4-B]并吲哚合成路线 （共 42 条）
反应条件
1: 37 percent / Na2WO4 hydrate, 36percent aq. H2O2 / methanol / 3 h / a) 0 deg C, 2 h, b) RT, 1 h
2: 48 h / 70 °C
3: 50 percent / 1,3,5-trimethyl-benzene / 4 h / Heating
View Scheme
参考文献
Brandi; Garro; Guarna; Goti; Cordero; De Sarlo
Journal of Organic Chemistry, 1988 , vol. 53, # 11 p. 2430 - 2434
反应条件
1: 70 percent / Cu2O / toluene / Heating
2: 85 percent / KH, TMEDA
3: 1.) n-BuLi / 1.) -78 deg C, THF, 1 h, 2.) -78 deg C, 30 min
4: 1.) N2H4, 2.) 10percentHCl / 1.) 2 h, ethanol-water-acetic acid, 2.) 2 h
View Scheme
参考文献
Loewe, Mallory F.; Meyers, A. I.
Tetrahedron Letters, 1985 , vol. 26, # 28 p. 3291 - 3294
