1,2,3,4-四氢-9H-吡啶[3,4-B]并吲哚合成路线 （共 42 条）
反应条件
1: 380 mg / Pd(OAc)2; PPh3; CO / acetonitrile / 15 h / 70 °C / 3040 Torr 2: 91 percent / ammonium formate / Pd(OH)2/C / methanol / 3.5 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 59, # 29 p. 5507 - 5514
反应条件
hydrogen; palladium on activated charcoal in 2,2,2-trifluoroethanol 5 h;
参考文献
Bailey, Patrick D.; Beard, Mark A.; Dang, Hoa P.T.; Phillips, Theresa R.; Price, Richard A.; Whittaker, James H.
Tetrahedron Letters, 2008 , vol. 49, # 13 p. 2150 - 2153
反应条件
acetic acid in acetonitrile 5 h; Heating;
参考文献
Hiemstra, H. C.; Bieraeugel, H.; Wijnberg, M.; Pandit, U. K.
Tetrahedron, 1983 , vol. 39, # 23 p. 3981 - 3986
反应条件
hydrogenchloride; water 0.5 h; Heating;
参考文献
Gynther, Jukka
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1988 , vol. 42, # 7 p. 433 - 441
反应条件
acetate buffer in water T=105°C; Pictet-Spengler cyclization; 4 h;
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 48, # 5 p. 323 - 330
反应条件
1: 58 percent / tetrahydrofuran / 1 h / -60 °C 2: 48 percent / dimethylformamide; triethylamine; pyridine / 1 h / 90 °C 3: 77 percent / MeLi / tetrahydrofuran; diethyl ether / 1 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 39, # 22 p. 3767 - 3776
反应条件
1: 58 percent / tetrahydrofuran / 1 h / -60 °C 2: 48 percent / dimethylformamide; triethylamine; pyridine / 1 h / 90 °C 3: 77 percent / MeLi / tetrahydrofuran; diethyl ether / 1 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 39, # 22 p. 3767 - 3776
反应条件
1: 48 percent / dimethylformamide; triethylamine; pyridine / 1 h / 90 °C 2: 77 percent / MeLi / tetrahydrofuran; diethyl ether / 1 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 39, # 22 p. 3767 - 3776
反应条件
1: 80 percent / N--chlorosuccinimide, NaOc / acetone / 1 h / 0 °C 2: 58 percent / tetrahydrofuran / 1 h / -60 °C 3: 48 percent / dimethylformamide; triethylamine; pyridine / 1 h / 90 °C 4: 77 percent / MeLi / tetrahydrofuran; diethyl ether / 1 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 39, # 22 p. 3767 - 3776
反应条件
1: 99 percent / Na2CO3 / diethyl ether / 24 h / Ambient temperature 2: 58 percent / tetrahydrofuran / 1 h / -60 °C 3: 48 percent / dimethylformamide; triethylamine; pyridine / 1 h / 90 °C 4: 77 percent / MeLi / tetrahydrofuran; diethyl ether / 1 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 39, # 22 p. 3767 - 3776
