1-氯-1,1,2,2,3,3,4,4,5,5,6,6-十二氟-6-碘己烷合成路线 （共 53 条）
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16486-97-81-氯-1,1,2,2,3,3,4,4,5,5,6,6-十二氟-6-碘己烷
反应条件
iodine in dichloromethane T=-20°C; 0.5 h;
参考文献
Huang, Wei-Yuan; Hu, Li-Qing
Journal of Fluorine Chemistry, 1989 , vol. 44, p. 25 - 44
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16486-97-81-氯-1,1,2,2,3,3,4,4,5,5,6,6-十二氟-6-碘己烷
反应条件
sodium peroxodisulphate; iodine in water; dimethyl sulfoxide T=20°C; 1 h;
参考文献
Cao, Hai-Ping; Chen, Qing-Yun
Journal of Fluorine Chemistry, 2007 , vol. 128, # 10 p. 1187 - 1190
→
16486-97-81-氯-1,1,2,2,3,3,4,4,5,5,6,6-十二氟-6-碘己烷+
参考文献
Hu, Chang-Ming; Qing, Feng-Ling
Journal of Organic Chemistry, 1991 , vol. 56, # 22 p. 6348 - 6351
→
16486-97-81-氯-1,1,2,2,3,3,4,4,5,5,6,6-十二氟-6-碘己烷+
反应条件
copper T=80 - 90°C; 1 h; further reagent ratio; Product distribution;
参考文献
Chen, Qing-Yun; Su, De-Bao; Yang, Zhen-Yu; Zhu, Rong-Xian
Journal of Fluorine Chemistry, 1987 , vol. 36, p. 483 - 489
16486-97-81-氯-1,1,2,2,3,3,4,4,5,5,6,6-十二氟-6-碘己烷
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反应条件
hydroxymethanesulfinic acid sodium salt; sodium hydrogencarbonate in water; acetonitrile T=65°C; 4 h;
参考文献
Huang, Bing-Nan; Liu, Jin-Tao
Journal of Fluorine Chemistry, 1993 , vol. 64, # 1-2 p. 37 - 46
16486-97-81-氯-1,1,2,2,3,3,4,4,5,5,6,6-十二氟-6-碘己烷
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反应条件
magnesium in N,N-dimethyl-formamide T=80°C; 15 h; Yields of byproduct given;
参考文献
CHEN, Quing-Yun; QIU, Zai-Ming
Journal of Fluorine Chemistry, 1988 , vol. 39, p. 289 - 292
16486-97-81-氯-1,1,2,2,3,3,4,4,5,5,6,6-十二氟-6-碘己烷
→
反应条件
magnesium in N,N-dimethyl-formamide T=80°C; 15 h; Yield given. Yields of byproduct given;
参考文献
CHEN, Quing-Yun; QIU, Zai-Ming
Journal of Fluorine Chemistry, 1988 , vol. 39, p. 289 - 292
16486-97-81-氯-1,1,2,2,3,3,4,4,5,5,6,6-十二氟-6-碘己烷
→
反应条件
1: Na2S2O4 / dimethylsulfoxide / 100 °C 2: 54 percent / Na2S2O8; iodine / H2O; dimethylsulfoxide / 1 h / 20 °C View Scheme
参考文献
Cao, Hai-Ping; Chen, Qing-Yun
Journal of Fluorine Chemistry, 2007 , vol. 128, # 10 p. 1187 - 1190
16486-97-81-氯-1,1,2,2,3,3,4,4,5,5,6,6-十二氟-6-碘己烷+
→
反应条件
sodium hydride 1.) DMF, 2.) DMF, 70 deg C, 10h, irradiation; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Chen, Qing-Yun; Chen, Mei-Jin
Journal of Fluorine Chemistry, 1991 , vol. 51, # 1 p. 21 - 32
16486-97-81-氯-1,1,2,2,3,3,4,4,5,5,6,6-十二氟-6-碘己烷
→
反应条件
sodium; ethyl acetoacetate in ethanol; N,N-dimethyl-formamide T=75°C; 10 h;
参考文献
Journal of Fluorine Chemistry, , vol. 35, p. 343
