5-氨基苯并呋喃-2-羧酸甲酯合成路线 （共 5 条）
反应条件
hydrogen; 5-palladium/activated carbon in methanol P=760.051 Torr; 4 h;
参考文献
STERIX LIMITED
Patent: WO2005/42513 A1, 2005 ;
Location in patent: Page/Page column 60 ;
反应条件
hydrogenchloride in methanol 20 h; Reflux;
参考文献
ERREGIERRE S.p.A.; Ferrari, Massimo; De Zani, Daniele; Bonaldi, Matteo
Patent: EP2647625 A1, 2013 ;
Location in patent: Paragraph 0049; 0050; 0051 ;
反应条件
1: 68 percent / K2CO3; Bu4NBr / toluene / 20 h / Heating 2: 98 percent / H2 / Pd/C / ethyl acetate / 8 h / 760.05 Torr View Scheme
参考文献
Boger, Dale L.; Fink, Brian E.; Hedrick, Michael P.
Journal of the American Chemical Society, 2000 , vol. 122, # 27 p. 6382 - 6394
反应条件
1: sodium acetate / water / 1 h / |Reflux 2: sodium hydrogencarbonate; potassium iodide / N,N-dimethyl acetamide / 28 h / 75 °C 3: ammonium chloride / N,N-dimethyl acetamide / 7 h / 100 °C 4: 5 palladium on charcoal; hydrogen / methanol / 2 h / 15 - 30 °C / 1125.11 Torr 5: ammonia / methanol / 20 h / 20 °C View Scheme
参考文献
SYMED LABS LIMITED; MOHAN RAO, Dodda; JITHENDER, Aadepu
Patent: WO2014/6637 A2, 2014 ;
反应条件
1: tributyl-amine / 43 h / 73 - 77 °C 2: sulfuric acid / 0.25 h / 25 - 102 °C 3: ammonia / methanol / 25 - 30 °C View Scheme
