2,3,3-三甲基-3H-吲哚合成路线 （共 91 条）
反应条件
liquid 1-butyl-3-methylimidazolium hydrosulfate T=70°C; Fischer indole synthesis; 2 h;
参考文献
Xu, Dan-Qian; Yang, Wen-Long; Luo, Shu-Ping; Wang, Bing-Tao; Wu, Jian; Xu, Zhen-Yuan
European Journal of Organic Chemistry, 2007 , # 6 p. 1007 - 1012
反应条件
acetic acid Fischer Indole Synthesis; 12 h; RefluxInert atmosphere;
参考文献
Gu, Jiamin; Anumala, Upendra Rao; Lo Monte, Fabio; Kramer, Thomas; Heyny Von Haussen, Roland; Hoelzer, Jana; Goetschy-Meyer, Valerie; Mall, Gerhard; Hilger, Ingrid; Czech, Christian; Schmidt, Boris
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 24 p. 7667 - 7671
反应条件
hydrogenchloride in water 1 h; Reflux;
参考文献
Roxburgh, Craig J.; Sammes, Peter G.; Abdullah, Ayse
Dyes and Pigments, 2011 , vol. 90, # 2 p. 146 - 162
参考文献
Bayer Aktiengesellschaft
Patent: US5179211 A1, 1993 ;
参考文献
Chisso Corporation
Patent: US4211704 A1, 1980 ;
反应条件
lithium chloride; zinc(II) chloride in paraffin 1.) 10 h, 190 degC, 2.) 6 h, 200 - 205 degC;
参考文献
Laas, Harald; Nissen, Axel; Nuerrenbach, Axel
Synthesis, 1981 , # 12 p. 958 - 959
反应条件
hydrogenchloride in methanol 25 h; Heating;
参考文献
Tetrahedron, , vol. 46, # 23 p. 7865 - 7872
反应条件
1: 76 percent / hydrogen / W-2 Raney nickel / methanol / 760 Torr / Ambient temperature 2: toluene / 5 h / Heating 3: 95 percent / CHCl3 / Ambient temperature 4: 92 percent / hydrogen / W-2 Raney nickel / methanol / 760 Torr / Ambient temperature 5: 80 percent / 30percent hydrochloric acid / methanol / 25 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 46, # 23 p. 7865 - 7872
反应条件
1: 92 percent / hydrogen / W-2 Raney nickel / methanol / 760 Torr / Ambient temperature 2: 80 percent / 30percent hydrochloric acid / methanol / 25 h / Heating 3: 99 percent / Et3N / benzene / 24 h / Ambient temperature 4: 76 percent / hydrogen / W-2 Raney nickel / methanol / 760 Torr / Ambient temperature 5: toluene / 5 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 46, # 23 p. 7865 - 7872
反应条件
1: 82 percent / hydrogen / W-2 Raney nickel / methanol / 760 Torr / Ambient temperature 2: 20 percent / 30percent hydrochloric acid / methanol / 25 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 46, # 23 p. 7865 - 7872
