5'-O-[双(4-甲氧基苯基)苯基甲基]-2'-O-(2-甲氧基乙基)-5-甲基尿苷合成路线 （共 2 条）
反应条件
1: With dichloro-acetic acid; pyrrole in dichloromethane 2: With triethylamine in methanol; dichloromethane
参考文献
Banerjee, Shyamapada; Srishylam; Rajendra Prasad; Migawa, Michael T.; Swayze, Eric E.; Sanghvi, Yogesh S.
Tetrahedron Letters, 2012 , vol. 53, # 35 p. 4669 - 4672
反应条件
1.1: trimethylsilyl chloride; triethylamine / acetonitrile / -10 - 5 °C
1.2: phosphorus oxychloride; 1,2,4-triazole / -20 - 5 °C
1.3: aq. NH3 / dioxane / 25 °C
2.1: dimethylformamide / 24 h / 25 °C
View Scheme
参考文献
Ross, Bruce S.; Song, Quanlai; Han, Mingming
Nucleosides, Nucleotides and Nucleic Acids, 2005 , vol. 24, # 5-7 p. 815 - 818
