反应条件
1: 3-(4-chloro-butyl)-5-cyanoindole With sodium iodide in N,N-dimethyl-formamide T=25 - 30°C; 0.25 h; 2: 1-(2-aminocarbonylbenzofuran-5-yl)piperazine With tetrabutylammomium bromide; sodium hydrogencarbonate in N,N-dimethyl-formamide T=110 - 115°C; 1.25 h; Reagent/catalystTemperatureTimeSolvent;
参考文献
DR.REDDYS LABORATORIES LIMITED; IQBAL, Javed; ORUGANTI, Srinivas; RAPOLU, Rajesh Kumar; PEDDY, Vishweshwar; BOGE, Rajesham; PATHIVADA, Deepika; VELAGA, Dharma Jagannadha Rao; YARRAGUNTLA, Sesha Reddy; BADDAM, Sudhakar Reddy; NAREDLA, Anitha; DONIPARTHI, Kiran Kumar; NADGOUD, Ramesh Kumar; PAGADALA, Narasimha Rao; UNNIARAN, Syam Kumar; RAMAKRISHNAN, Srividya
Patent: WO2013/168126 A1, 2013 ;
Location in patent: Page/Page column 75-78 ;