(4-甲基哌啶-4-基)氨基甲酸叔丁酯合成路线 （共 7 条）
反应条件
hydrogen; 10 Pd(OH)2/C in methanol T=20°C; P=3040.2 Torr; 2 h;
参考文献
WO2005/42533 A2, ;
Page/Page column 65-66 ;
WO 2005/042533 A2
反应条件
water; sodium hydroxide in ethanol 8 h; Reflux;
参考文献
UBE INDUSTRIES, LTD.
Patent: US2012/149902 A1, 2012 ;
Location in patent: Page/Page column 24 ;
反应条件
triethylamine in toluene
参考文献
US5502063 A1, ;
US 5502063 A
反应条件
1.1: triethylamine / dichloromethane / Cooling with ice 2.1: diisopropylamine; n-butyllithium / hexane; tetrahydrofuran / 1.17 h / -78 - 0 °C 2.2: -78 - 20 °C 3.1: sodium hydroxide; water / ethanol / 5 h / 50 °C 3.2: pH 1 4.1: triethylamine; diphenylphosphoranyl azide / toluene / 3 h / Reflux 4.2: 0.33 h / 20 °C 5.1: sodium hydroxide; water / ethanol / 8 h / Reflux View Scheme
反应条件
1.1: diisopropylamine; n-butyllithium / hexane; tetrahydrofuran / 1.17 h / -78 - 0 °C 1.2: -78 - 20 °C 2.1: sodium hydroxide; water / ethanol / 5 h / 50 °C 2.2: pH 1 3.1: triethylamine; diphenylphosphoranyl azide / toluene / 3 h / Reflux 3.2: 0.33 h / 20 °C 4.1: sodium hydroxide; water / ethanol / 8 h / Reflux View Scheme
反应条件
1.1: sodium hydroxide; water / ethanol / 5 h / 50 °C 1.2: pH 1 2.1: triethylamine; diphenylphosphoranyl azide / toluene / 3 h / Reflux 2.2: 0.33 h / 20 °C 3.1: sodium hydroxide; water / ethanol / 8 h / Reflux View Scheme
反应条件
1.1: triethylamine; diphenylphosphoranyl azide / toluene / 3 h / Reflux 1.2: 0.33 h / 20 °C 2.1: sodium hydroxide; water / ethanol / 8 h / Reflux View Scheme
