7-苄氧基-4-氯-6-甲氧基喹唑啉合成路线 （共 21 条）
反应条件
sodium hydroxide; N-ethyl-N,N-diisopropylamine; trichlorophosphate
参考文献
KIRIN BEER KABUSHIKI KAISHA
Patent: EP1153920 A1, 2001 ;
反应条件
thionyl chloride in N,N-dimethyl-formamide
反应条件
1: 100 percent / HNO3; Ac2O / 3 h / 20 °C 2: 97 percent / Fe; FeCl3 / acetic acid; H2O; ethanol / 4 h / 20 °C 3: 87 percent / 5 h / 190 °C 4: 92 percent / POCl3 / 3 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 46, # 23 p. 4910 - 4925
反应条件
1: 97 percent / Fe; FeCl3 / acetic acid; H2O; ethanol / 4 h / 20 °C 2: 87 percent / 5 h / 190 °C 3: 92 percent / POCl3 / 3 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 46, # 23 p. 4910 - 4925
反应条件
1: K2CO3 / dimethylformamide / 20 °C 2: 100 percent / HNO3; Ac2O / 3 h / 20 °C 3: 97 percent / Fe; FeCl3 / acetic acid; H2O; ethanol / 4 h / 20 °C 4: 87 percent / 5 h / 190 °C 5: 92 percent / POCl3 / 3 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 46, # 23 p. 4910 - 4925
反应条件
1: 87 percent / 5 h / 190 °C 2: 92 percent / POCl3 / 3 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 46, # 23 p. 4910 - 4925
反应条件
1: formamide 2: thionyl chloride / N,N-dimethyl-formamide View Scheme
参考文献
Tetrahedron Letters, , vol. 52, # 10 p. 1053 - 1056
反应条件
1: sodium tetrahydroborate; NiII chloride hexahydrate 2: formamide 3: thionyl chloride / N,N-dimethyl-formamide View Scheme
参考文献
Tetrahedron Letters, , vol. 52, # 10 p. 1053 - 1056
反应条件
1: potassium carbonate / acetone 2: nitric acid / acetic acid 3: sodium tetrahydroborate; NiII chloride hexahydrate 4: formamide 5: thionyl chloride / N,N-dimethyl-formamide View Scheme
参考文献
Tetrahedron Letters, , vol. 52, # 10 p. 1053 - 1056
反应条件
1: nitric acid / acetic acid 2: sodium tetrahydroborate; NiII chloride hexahydrate 3: formamide 4: thionyl chloride / N,N-dimethyl-formamide View Scheme
参考文献
Tetrahedron Letters, , vol. 52, # 10 p. 1053 - 1056
