3-(1,3-苯并二氧戊环-5-基)-5-羟基-5-(4-甲氧基苯基)-4-(3,4,5-三甲氧基苄基)-2(5H)-呋喃酮合成路线 （共 4 条）
反应条件
1: HOAc / 2-ethoxy-ethanol / 100 °C 2: p-TsOH / Heating 3: 1.) NaOMe, 2.) AcOH / 1.) MeOH, 60 deg C, 24 h, 2.) MeOH, reflux, 24 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 42, # 12 p. 2162 - 2168
反应条件
1: p-TsOH / Heating 2: 1.) NaOMe, 2.) AcOH / 1.) MeOH, 60 deg C, 24 h, 2.) MeOH, reflux, 24 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 42, # 12 p. 2162 - 2168
反应条件
1: NaOH / ethanol 2: HOAc / 2-ethoxy-ethanol / 100 °C 3: p-TsOH / Heating 4: 1.) NaOMe, 2.) AcOH / 1.) MeOH, 60 deg C, 24 h, 2.) MeOH, reflux, 24 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 42, # 12 p. 2162 - 2168
反应条件
sodium methylate; acetic acid 1.) MeOH, reflux, 4 h, 2.) MeOH, reflux, 18 h; Multistep reaction;
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 8 p. 1259 - 1263
