5-苯基-1H-吡咯-3-羧酸乙酯合成路线 （共 15 条）
反应条件
hydrogen; 10 palladium on active carbon in ethanol
T=20°C; Dehalogenation; P=3040 Torr;
参考文献
Pinna; Curzu; Sechi; Chelucci; Maciocco
Farmaco (Societa chimica italiana : 1989), 1999 , vol. 54, # 8 p. 542 - 550
反应条件
hydrogen; 10 palladium on active carbon in ethanol
T=20°C; Dehalogenation; P=3040 Torr;
参考文献
Pinna; Curzu; Sechi; Chelucci; Maciocco
Farmaco (Societa chimica italiana : 1989), 1999 , vol. 54, # 8 p. 542 - 550
反应条件
PPh3 gold(I) chloro complex; silver trifluoromethanesulfonate in toluene
T=100°C; 12 h;
参考文献
Ngwerume, Simbarashe; Lewis, William; Camp, Jason E.
Journal of Organic Chemistry, 2013 , vol. 78, # 3 p. 920 - 934
反应条件
triethylamine in toluene
T=110°C; 72 h;
参考文献
Palacios, Francisco; Herran, Esther; Rubiales, Gloria
Heterocycles, 2002 , vol. 58, p. 89 - 92
反应条件
sodium hydride in diethyl ether; dimethyl sulfoxide
0.5 h; Ambient temperature;
参考文献
Di Santo; Costi; Massa; Artico
Synthetic Communications, 1995 , vol. 25, # 6 p. 795 - 802
反应条件
1: 80 percent / HCl / diethyl ether / 0 - 20 °C
2: 98 percent / H2 / 10 percent Pd/C / ethanol / 20 °C / 3040 Torr
View Scheme
参考文献
Pinna; Curzu; Sechi; Chelucci; Maciocco
Farmaco (Societa chimica italiana : 1989), 1999 , vol. 54, # 8 p. 542 - 550
反应条件
1.1: EtONa / ethanol
1.2: 50.3 percent / tetrahydrofuran / 20 °C
2.1: 80 percent / HCl / diethyl ether / 0 - 20 °C
3.1: 98 percent / H2 / 10 percent Pd/C / ethanol / 20 °C / 3040 Torr
View Scheme
参考文献
Pinna; Curzu; Sechi; Chelucci; Maciocco
Farmaco (Societa chimica italiana : 1989), 1999 , vol. 54, # 8 p. 542 - 550
反应条件
1.1: EtONa / ethanol
1.2: 50.3 percent / tetrahydrofuran / 20 °C
2.1: 80 percent / HCl / diethyl ether / 0 - 20 °C
3.1: 98 percent / H2 / 10 percent Pd/C / ethanol / 20 °C / 3040 Torr
View Scheme
参考文献
Pinna; Curzu; Sechi; Chelucci; Maciocco
Farmaco (Societa chimica italiana : 1989), 1999 , vol. 54, # 8 p. 542 - 550
反应条件
1.1: EtONa / ethanol
1.2: 82 percent / tetrahydrofuran / 20 °C
2.1: 82 percent / HCl / diethyl ether / 0 - 20 °C
3.1: 100 percent / H2 / 10 percent Pd/C / ethanol / 20 °C / 3040 Torr
View Scheme
参考文献
Pinna; Curzu; Sechi; Chelucci; Maciocco
Farmaco (Societa chimica italiana : 1989), 1999 , vol. 54, # 8 p. 542 - 550
反应条件
1: 82 percent / HCl / diethyl ether / 0 - 20 °C
2: 100 percent / H2 / 10 percent Pd/C / ethanol / 20 °C / 3040 Torr
View Scheme
参考文献
Pinna; Curzu; Sechi; Chelucci; Maciocco
Farmaco (Societa chimica italiana : 1989), 1999 , vol. 54, # 8 p. 542 - 550
