N-(4-硝基苯基)甲酰胺合成路线 （共 53 条）
反应条件
silica-bonded N-propyl sulfamic acid T=20°C; 8 h; chemoselective reaction;
参考文献
Niknam, Khodabakhsh; Saberi, Dariush
Tetrahedron Letters, 2009 , vol. 50, # 37 p. 5210 - 5214
反应条件
water; acetic acid in tetrahydrofuran Ambient temperature;
参考文献
Ono; Araya; Todoriki; Tamura
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 7 p. 1824 - 1831
反应条件
tin in toluene Heating;
参考文献
Hrvatin, Paul; Sykes, Andrew G.
Synlett, 1997 , vol. 1997, # 9 p. 1069 - 1070
反应条件
1: 85 percent / Et3N / benzene / 1 h / Heating 2: 1.) LDA, HMPA, 2.) HMPA / 1.) THF, hexane, 0 deg C, 2.) THF, 1 h, room temperature 3: 1 N sodium ethoxide / ethanol; tetrahydrofuran / 4 h / Ambient temperature 4: water, AcOH / tetrahydrofuran / Ambient temperature View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 38, # 7 p. 1824 - 1831
反应条件
1: 1.) LDA, HMPA, 2.) HMPA / 1.) THF, hexane, 0 deg C, 2.) THF, 1 h, room temperature 2: 1 N sodium ethoxide / ethanol; tetrahydrofuran / 4 h / Ambient temperature 3: water, AcOH / tetrahydrofuran / Ambient temperature View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 38, # 7 p. 1824 - 1831
反应条件
1: 1.) n-BuLi, diisopropylamine / 1.) THF, hexane, 0 deg C, 2.) 45 min, room temperature 2: 78 percent / 1 N NaOH / tetrahydrofuran / 1.5 h / Ambient temperature 3: 85 percent / Et3N / benzene / 1 h / Heating 4: 1.) LDA, HMPA, 2.) HMPA / 1.) THF, hexane, 0 deg C, 2.) THF, 1 h, room temperature 5: 1 N sodium ethoxide / ethanol; tetrahydrofuran / 4 h / Ambient temperature 6: water, AcOH / tetrahydrofuran / Ambient temperature View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 38, # 7 p. 1824 - 1831
反应条件
1: 78 percent / 1 N NaOH / tetrahydrofuran / 1.5 h / Ambient temperature 2: 85 percent / Et3N / benzene / 1 h / Heating 3: 1.) LDA, HMPA, 2.) HMPA / 1.) THF, hexane, 0 deg C, 2.) THF, 1 h, room temperature 4: 1 N sodium ethoxide / ethanol; tetrahydrofuran / 4 h / Ambient temperature 5: water, AcOH / tetrahydrofuran / Ambient temperature View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 38, # 7 p. 1824 - 1831
反应条件
in toluene T=50°C; 3 h;
参考文献
Hu, Bin; Li, Yunfeng; Li, Zhongjun; Meng, Xiangbao
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 25 p. 4138 - 4141
反应条件
in toluene 0.5 h; Heating;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 1 p. 71 - 77
反应条件
water; acetic acid in tetrahydrofuran Ambient temperatureother N1-alkyl-N2-(p-nitrophenyl)formamidines; Product distribution;
参考文献
Ono; Araya; Todoriki; Tamura
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 7 p. 1824 - 1831
