1.1: boron tribromide / dichloromethane / 0.5 h / -20 - -10 °C 2.1: potassium carbonate / 1-methyl-pyrrolidin-2-one / 5 h / 115 - 120 °C 2.2: 20 °C / pH 3 - 4 / Acidic conditions 3.1: sulfuric acid / 1,4-dioxane; water / 5 h / 95 - 100 °C 4.1: acetic acid / methanol / 1 h / 20 °C 4.2: 25 - 45 °C 5.1: sodium hydroxide; water / methanol / 6 h / 20 °C 6.1: sodium hydroxide; dihydrogen peroxide / dimethyl sulfoxide / 6 h / 20 °C View Scheme

1.1: potassium carbonate / 1-methyl-pyrrolidin-2-one / 5 h / 115 - 120 °C 1.2: 20 °C / pH 3 - 4 / Acidic conditions 2.1: sulfuric acid / 1,4-dioxane; water / 5 h / 95 - 100 °C 3.1: acetic acid / methanol / 1 h / 20 °C 3.2: 25 - 45 °C 4.1: sodium hydroxide; water / methanol / 6 h / 20 °C 5.1: sodium hydroxide; dihydrogen peroxide / dimethyl sulfoxide / 6 h / 20 °C View Scheme

1.1: ethanol; sodium tetrahydroborate / tetrahydrofuran / 1.5 h / 20 °C / cooling with ice 1.2: 1 h / pH 4 2.1: trichlorophosphate / 0.83 h / cooling with ice 2.2: 2.58 h / 50 °C 3.1: hydroxylamine hydrochloride; pyridine / tetrahydrofuran / 1 h / 50 °C 3.2: 3.5 h / 50 °C / Reflux 4.1: hydrogen / palladium 10 on activated carbon / methanol / 1 h / 40 °C / 750.08 Torr 5.1: water; acetone / 3.25 h / 20 °C / Reflux 6.1: sodium carbonate / water / pH 8 - 9 7.1: sodium carbonate / ethanol; tert-butyl alcohol / 42 h / 50 - 90 °C 8.1: sodium hydroxide; water / methanol / 1.25 h / 20 °C / cooling with ice 9.1: sodium hydroxide; dihydrogen peroxide / water; dimethyl sulfoxide / 2.25 h / 20 - 25 °C View Scheme

1.1: trichlorophosphate / 0.83 h / cooling with ice 1.2: 2.58 h / 50 °C 2.1: hydroxylamine hydrochloride; pyridine / tetrahydrofuran / 1 h / 50 °C 2.2: 3.5 h / 50 °C / Reflux 3.1: hydrogen / palladium 10 on activated carbon / methanol / 1 h / 40 °C / 750.08 Torr 4.1: water; acetone / 3.25 h / 20 °C / Reflux 5.1: sodium carbonate / water / pH 8 - 9 6.1: sodium carbonate / ethanol; tert-butyl alcohol / 42 h / 50 - 90 °C 7.1: sodium hydroxide; water / methanol / 1.25 h / 20 °C / cooling with ice 8.1: sodium hydroxide; dihydrogen peroxide / water; dimethyl sulfoxide / 2.25 h / 20 - 25 °C View Scheme

1.1: hydroxylamine hydrochloride; pyridine / tetrahydrofuran / 1 h / 50 °C 1.2: 3.5 h / 50 °C / Reflux 2.1: hydrogen / palladium 10 on activated carbon / methanol / 1 h / 40 °C / 750.08 Torr 3.1: water; acetone / 3.25 h / 20 °C / Reflux 4.1: sodium carbonate / water / pH 8 - 9 5.1: sodium carbonate / ethanol; tert-butyl alcohol / 42 h / 50 - 90 °C 6.1: sodium hydroxide; water / methanol / 1.25 h / 20 °C / cooling with ice 7.1: sodium hydroxide; dihydrogen peroxide / water; dimethyl sulfoxide / 2.25 h / 20 - 25 °C View Scheme

1: hydrogen / palladium 10 on activated carbon / methanol / 1 h / 40 °C / 750.08 Torr 2: water; acetone / 3.25 h / 20 °C / Reflux 3: sodium carbonate / water / pH 8 - 9 4: sodium carbonate / ethanol; tert-butyl alcohol / 42 h / 50 - 90 °C 5: sodium hydroxide; water / methanol / 1.25 h / 20 °C / cooling with ice 6: sodium hydroxide; dihydrogen peroxide / water; dimethyl sulfoxide / 2.25 h / 20 - 25 °C View Scheme

1.1: trichlorophosphate / 0.67 h / cooling with ice 1.2: 3 h / 20 °C 1.3: 0.5 h 2.1: ammonium acetate / 1 h / Reflux 3.1: ethanol; sodium tetrahydroborate / tetrahydrofuran / 1.5 h / 20 °C / cooling with ice 3.2: 1 h / pH 4 4.1: trichlorophosphate / 0.83 h / cooling with ice 4.2: 2.58 h / 50 °C 5.1: hydroxylamine hydrochloride; pyridine / tetrahydrofuran / 1 h / 50 °C 5.2: 3.5 h / 50 °C / Reflux 6.1: hydrogen / palladium 10 on activated carbon / methanol / 1 h / 40 °C / 750.08 Torr 7.1: water; acetone / 3.25 h / 20 °C / Reflux 8.1: sodium carbonate / water / pH 8 - 9 9.1: sodium carbonate / ethanol; tert-butyl alcohol / 42 h / 50 - 90 °C 10.1: sodium hydroxide; water / methanol / 1.25 h / 20 °C / cooling with ice 11.1: sodium hydroxide; dihydrogen peroxide / water; dimethyl sulfoxide / 2.25 h / 20 - 25 °C View Scheme

1.1: ammonium acetate / 1 h / Reflux 2.1: ethanol; sodium tetrahydroborate / tetrahydrofuran / 1.5 h / 20 °C / cooling with ice 2.2: 1 h / pH 4 3.1: trichlorophosphate / 0.83 h / cooling with ice 3.2: 2.58 h / 50 °C 4.1: hydroxylamine hydrochloride; pyridine / tetrahydrofuran / 1 h / 50 °C 4.2: 3.5 h / 50 °C / Reflux 5.1: hydrogen / palladium 10 on activated carbon / methanol / 1 h / 40 °C / 750.08 Torr 6.1: water; acetone / 3.25 h / 20 °C / Reflux 7.1: sodium carbonate / water / pH 8 - 9 8.1: sodium carbonate / ethanol; tert-butyl alcohol / 42 h / 50 - 90 °C 9.1: sodium hydroxide; water / methanol / 1.25 h / 20 °C / cooling with ice 10.1: sodium hydroxide; dihydrogen peroxide / water; dimethyl sulfoxide / 2.25 h / 20 - 25 °C View Scheme

1.1: sodium hydrogencarbonate; sodium hypochlorite; potassium bromide; 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical / dichloromethane / 0 - 5 °C 2.1: acetic acid / methanol / 1 h / 20 °C 2.2: 25 - 45 °C 3.1: sodium hydroxide; water / methanol / 6 h / 20 °C 4.1: sodium hydroxide; dihydrogen peroxide / dimethyl sulfoxide / 6 h / 20 °C View Scheme

1.1: sulfuric acid / 1,4-dioxane; water / 5 h / 95 - 100 °C 2.1: acetic acid / methanol / 1 h / 20 °C 2.2: 25 - 45 °C 3.1: sodium hydroxide; water / methanol / 6 h / 20 °C 4.1: sodium hydroxide; dihydrogen peroxide / dimethyl sulfoxide / 6 h / 20 °C View Scheme