1-(4-氯苯甲酰基)-5-甲氧基-2-甲基-1H-吲哚-3-乙酸甲酯合成路线 （共 8 条）
反应条件
1: 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid With bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; triethylamine in dichloromethane 0.166667 h; Inert atmosphere; 2: methanol in dichloromethane 12 h; Inert atmosphere;
参考文献
Scholz, Matthias; Blobaum, Anna L.; Marnett, Lawrence J.; Hey-Hawkins, Evamarie
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 15 p. 4830 - 4837
反应条件
hydrogenchloride 2 h; Ambient temperature;
参考文献
Fronza; Mele; Redenti; Ventura
Journal of Organic Chemistry, 1996 , vol. 61, # 3 p. 909 - 914
反应条件
in methanol 720 h; Heating;
参考文献
Tetrahedron Letters, , vol. 38, # 4 p. 621 - 622
反应条件
1: 1.) MeMgCl, ZnCl2 / 1.) Et2O 2: 1.) KHMDS, HMPA / 1.) THF View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 6, # 19 p. 2263 - 2268
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; potassium hexamethylsilazane 1.) THF; Multistep reaction;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 6, # 19 p. 2263 - 2268
参考文献
Tetrahedron Letters, , vol. 38, # 4 p. 621 - 622
参考文献
Journal of Organometallic Chemistry, , vol. 524, # 1-2 p. 87 - 93
反应条件
hydrazine hydrate in ethanol 4 h; Heating;
参考文献
Sharma, Vibha; Khan
Pharmazie, 2003 , vol. 58, # 2 p. 99 - 103
