双(3-(三氟甲基)苯基)甲醇合成路线 （共 7 条）
反应条件
1: With sodium tetrahydroborate in methanol T=20°C; 24 h; 2: With water in methanol
参考文献
Hitchcock, Stephen; Amegadzie, Albert; Qian, Wenyuan; Xia, Xiaoyang; Harried, Scott S.
Patent: US2008/4289 A1, 2008 ;
Location in patent: Page/Page column 32 ;
反应条件
magnesium in diethyl ether 18 h; Heating;
参考文献
Streitwieser, Andrew Jr.; Vorpagel, Erich R.; Chen, Chia-Chung
Journal of the American Chemical Society, 1985 , vol. 107, # 24 p. 6970 - 6975
反应条件
1: 1-bromo-3-trifluoromethyl-benzene With n-butyllithium in diethyl ether T=-78°C; 1 h; 2: α,α,α-trifluoro-m-tolualdehyde in diethyl ether T=20°C; 2.5 h;
参考文献
Mills, Nancy S.; Tirla, Cornelia; Benish, Michele A.; Rakowitz, Amber J.; Bebell, Lisa M.; Hurd, Caroline M. M.; Bria, Anna L. M.
Journal of Organic Chemistry, 2005 , vol. 70, # 26 p. 10709 - 10716
反应条件
1: (i) Mg, I2, Et2O, (ii) /BRN= 1900390/ 2: Zn, NaOH / aq. ethanol / 2 h / Heating View Scheme
参考文献
Lichtenberger,J.; Weiss,F.
Bulletin de la Societe Chimique de France, 1962 , p. 587 - 593
参考文献
Mindl,J.; Vecera,M.
Collection of Czechoslovak Chemical Communications, 1973 , vol. 38, p. 3496 - 3505
反应条件
iodine; hypophosphorous acid in acetic acid T=60°C; 72 h;
参考文献
Gordon, Paul E.; Fry, Albert J.
Tetrahedron Letters, 2001 , vol. 42, # 5 p. 831 - 833
反应条件
oxalyl dichloride; dimethyl sulfoxide; triethylamine in dichloromethane T=20°C; Swern oxidation; 1 h;
参考文献
Mills, Nancy S.; Tirla, Cornelia; Benish, Michele A.; Rakowitz, Amber J.; Bebell, Lisa M.; Hurd, Caroline M. M.; Bria, Anna L. M.
Journal of Organic Chemistry, 2005 , vol. 70, # 26 p. 10709 - 10716
