甲基4-氨基-1-苄基-1,2,5,6-四氢吡啶-3-羧酸合成路线 （共 6 条）
反应条件
1: With ammonia in water T=50°C; 18 h; 2: With sodium tetrahydroborate in water T=0 - 20°C; 18 h;
参考文献
US2006/135561 A1, ;
Page/Page column 19 ;
反应条件
ammonium hydroxide; sodium carbonate in ethanol
反应条件
triethylamine in toluene T=100°C; 24 h;
参考文献
Furrer; Fehlhaber; Wagner
Journal of Heterocyclic Chemistry, 1994 , vol. 31, # 6 p. 1569 - 1575
反应条件
in 2-methoxy-ethanol Heating / reflux;
参考文献
WO2004/14384 A2, ;
Page/Page column 198-199 ;
WO 2004/014384 A2
反应条件
T=180°C; 0.666667 h;
参考文献
Journal of Heterocyclic Chemistry, , vol. 31, # 6 p. 1569 - 1575
反应条件
1: With trifluoroacetic acid in tetrahydrofuran
T=0 - 10°C; 0.25 h;
2: With sodium tetrahydroborate in tetrahydrofuran
T=0 - 10°C; 2.75 h;
参考文献
Boehringer, Markus; Hunziker, Daniel; Kuhn, Bernd; Loeffler, Bernd Michael; Luebbers, Thomas; Ricklin, Fabienne
Patent: US2006/135561 A1, 2006 ;
Location in patent: Page/Page column 19 ;
