3-亚甲基环丁烷羧酸甲酯合成路线 （共 17 条）
反应条件
(i) Ag2O, CCl4, (ii) /BRN= 102415/, Et2O; Multistep reaction;
参考文献
Musso,H. et al.
Chemische Berichte, 1967 , vol. 100, p. 3614 - 3624
反应条件
1: PhCOCl, HBr / CCl4 / Irradiation 2: aq. NaOH View Scheme
参考文献
Wiberg,K.B.; Connor,D.S.
Journal of the American Chemical Society, 1966 , vol. 88, p. 4437 - 4441
反应条件
hydrogen; platinum(IV) oxide in methanol
参考文献
Lampman,G.M. et al.
Journal of Organic Chemistry, 1967 , vol. 32, p. 3950 - 3955
反应条件
pyridine; ozone in dichloromethane T=-80°C;
参考文献
Hanack,M.; Riedlinger,K.
Chemische Berichte, 1967 , vol. 100, p. 2107 - 2116
反应条件
1: PhCOCl, HBr / CCl4 / Irradiation 2: aq. NaOH 3: Br2, HgO / CCl4 4: (i) Li-Hg, dioxane, (ii) Br2 View Scheme
参考文献
Wiberg,K.B.; Connor,D.S.
Journal of the American Chemical Society, 1966 , vol. 88, p. 4437 - 4441
反应条件
hydrogen bromide; benzoyl chloride in tetrachloromethane
Irradiation;
参考文献
Wiberg,K.B.; Connor,D.S.
Journal of the American Chemical Society, 1966 , vol. 88, p. 4437 - 4441
反应条件
1: With borane-THF in tetrahydrofuran
T=-10 - 20°C; 4 h;
2: With dihydrogen peroxide; sodium hydroxide in tetrahydrofuran
2 h;
参考文献
ACHAOGEN, INC.; KASAR, Ramesh; LINSELL, Martin Sheringham; AGGEN, James Bradley; LU, Qing (Jane); WANG, Dan; CHURCH, Tim; MOSER, Heinz E.; PATTEN, Phillip A.
Patent: WO2012/154204 A1, 2012 ;
Location in patent: Page/Page column 67; 68; 69 ;
