2-氯-6-甲氧基异烟酸合成路线 （共 14 条）
反应条件
1: concentrated H2SO4 2: palladium; aqueous methanol. KOH / Hydrogenation 3: concentrated H2SO4 View Scheme
参考文献
Okajima; Seki
Yakugaku Zasshi, 1953 , vol. 73, p. 845,846, 847
Chem.Abstr., 1954 , p. 10021
反应条件
boric acid trimethyl ester; dimethylsulfide borane complex in tetrahydrofuran
T=20°C; 16 h;
参考文献
Wild, Nicole; Groth, Ulrich
European Journal of Organic Chemistry, 2003 , # 22 p. 4445 - 4449
反应条件
1: BH3*THF / tetrahydrofuran / 0 - 20 °C
2: 45 percent / Pd(OAc)2; 1,3-bis(diphenylphosphino)propane; K2CO3 / dimethylformamide / 90 °C / 775.72 Torr
3: 74 percent / Ph3P; imidazole; CBr4 / tetrahydrofuran / 3.5 h / 20 °C
View Scheme
参考文献
Adamczyk, Maciej; Akireddy, Srinivasa Rao; Reddy, Rajarathnam E
Tetrahedron, 2002 , vol. 58, # 34 p. 6951 - 6963
反应条件
1: 86 percent / BH3*SMe2; B(OMe)3 / tetrahydrofuran / 16 h / 20 °C
2: 98 percent / PPh3; CBr4 / benzene / 16 h / 20 °C
View Scheme
参考文献
Adamczyk, Maciej; Akireddy, Srinivasa Rao; Reddy, Rajarathnam E
Tetrahedron, 2002 , vol. 58, # 34 p. 6951 - 6963
