4-氨基-3-氟-苯甲酸叔丁酯合成路线 (共 3 条)
反应条件
ammonium formate; palladium on activated charcoal in ethanol
参考文献
Springer; Niculescu-Duvaz; Pedley
Journal of Medicinal Chemistry, 1994 , vol. 37, # 15 p. 2361 - 2370
反应条件
1: 1.) BuLi / 1.) hexane, 20 deg C, 20 min, 2.) hexane, THF, 22 h 2: 98 percent / ammonium formate / 10percent Pd/C / ethanol View Scheme
参考文献
Springer; Niculescu-Duvaz; Pedley
Journal of Medicinal Chemistry, 1994 , vol. 37, # 15 p. 2361 - 2370
反应条件
1: 62 percent / SOCl2 / toluene / 3 h / Heating 2: 1.) BuLi / 1.) hexane, 20 deg C, 20 min, 2.) hexane, THF, 22 h 3: 98 percent / ammonium formate / 10percent Pd/C / ethanol View Scheme
参考文献
Springer; Niculescu-Duvaz; Pedley
Journal of Medicinal Chemistry, 1994 , vol. 37, # 15 p. 2361 - 2370