3,4-二甲基-2,5-二氢呋喃-2-酮合成路线 （共 17 条）
反应条件
tri-ruthenium(0)dodecacarbonyl; triethylamine in 1,4-dioxane T=100°C; P=7600 Torr; 8 h;
参考文献
Yoneda, Eiji; Zhang, Shi-Wei; Zhou, Da-Yang; Onitsuka, Kiyotaka; Takahashi, Shigetoshi
Journal of Organic Chemistry, 2003 , vol. 68, # 22 p. 8571 - 8576
反应条件
1: With sodium hydroxide; sodium tetrahydroborate in water T=20 - 30°C; 2.5 h; 2: With sulfuric acid in water T=90°C; 1 h;
参考文献
SYMRISE GMBH and CO. KG
Patent: WO2007/131834 A1, 2007 ;
Location in patent: Page/Page column 61 ;
反应条件
tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran T=55°C; P=760.051 Torr;
参考文献
Greco, George E.; Gleason, Brittany L.; Lowery, Tiffany A.; Kier, Matthew J.; Hollander, Lisa B.; Gibbs, Shoshanah A.; Worthy, Amanda D.
Organic Letters, 2007 , vol. 9, # 19 p. 3817 - 3820
反应条件
rhodium (II) acetate; hydrogen; triphenylphosphine in ethyl acetate T=90°C; P=20685.9 Torr; 18 h;
参考文献
Campi, Eva M.; Fallon, Gary D.; Jackson, W. Roy; Nilsson, Ylva
Australian Journal of Chemistry, 1992 , vol. 45, # 7 p. 1167 - 1178
反应条件
rhodium (II) acetate; hydrogen; triphenylphosphine in ethyl acetate T=90°C; P=2068.6 Torr; 20 h;
参考文献
Campi, Eva M.; Fallon, Gary D.; Jackson, W. Roy; Nilsson, Ylva
Australian Journal of Chemistry, 1992 , vol. 45, # 7 p. 1167 - 1178
反应条件
p-toluenesulfonic acid monohydrate T=150°C; 19 h;
参考文献
Bongards, Christian; Gaertner, Wolfgang
European Journal of Organic Chemistry, 2007 , # 34 p. 5749 - 5758
反应条件
sulfuric acid T=50°C; P=51754.1 Torr;
参考文献
Woo, Edmund P.; Cheng, Frank C.W.
Journal of Organic Chemistry, 1986 , vol. 51, # 19 p. 3706 - 3707
反应条件
1.1: methyllithium; HMPA / diethyl ether / 0.17 h / -20 °C 1.2: 84 percent / diethyl ether / 0.08 h / -20 °C 2.1: NaH / tetrahydrofuran / 0.75 h / Heating 2.2: LiAlH4 / tetrahydrofuran / 48 h / Heating 3.1: 978 mg / pyridine / CH2Cl2 / 0.17 h / 0 °C 4.1: 35 percent / (Ph3P)4Pd / tetrahydrofuran / 55 °C / 760.05 Torr View Scheme
参考文献
Greco, George E.; Gleason, Brittany L.; Lowery, Tiffany A.; Kier, Matthew J.; Hollander, Lisa B.; Gibbs, Shoshanah A.; Worthy, Amanda D.
Organic Letters, 2007 , vol. 9, # 19 p. 3817 - 3820
反应条件
1: 978 mg / pyridine / CH2Cl2 / 0.17 h / 0 °C 2: 35 percent / (Ph3P)4Pd / tetrahydrofuran / 55 °C / 760.05 Torr View Scheme
参考文献
Greco, George E.; Gleason, Brittany L.; Lowery, Tiffany A.; Kier, Matthew J.; Hollander, Lisa B.; Gibbs, Shoshanah A.; Worthy, Amanda D.
Organic Letters, 2007 , vol. 9, # 19 p. 3817 - 3820
反应条件
1.1: NaH / tetrahydrofuran / 0.75 h / Heating 1.2: LiAlH4 / tetrahydrofuran / 48 h / Heating 2.1: 978 mg / pyridine / CH2Cl2 / 0.17 h / 0 °C 3.1: 35 percent / (Ph3P)4Pd / tetrahydrofuran / 55 °C / 760.05 Torr View Scheme
参考文献
Greco, George E.; Gleason, Brittany L.; Lowery, Tiffany A.; Kier, Matthew J.; Hollander, Lisa B.; Gibbs, Shoshanah A.; Worthy, Amanda D.
Organic Letters, 2007 , vol. 9, # 19 p. 3817 - 3820
