2-(2-(1H-吲哚-3-基)乙基)异吲哚啉-1,3-二酮合成路线 （共 21 条）
参考文献
Feng, Pengju; Fan, Yukai; Xue, Fazhen; Liu, Weigang; Li, Songlei; Shi, Yian
Organic Letters, 2011 , vol. 13, # 21 p. 5827 - 5829
反应条件
hydrogen; toluene-4-sulfonic acid; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; [rhodium(I)(carbonyl)2(acetylacetonate)] in tetrahydrofuran T=60 - 100°C; P=15001.2 Torr; 68 h;
参考文献
Koehling, Petra; Schmidt, Axel M.; Eilbracht, Peter
Organic Letters, 2003 , vol. 5, # 18 p. 3213 - 3216
参考文献
Loegers, Michael; Overman, Larry E.; Welmaker, Gregory S.
Journal of the American Chemical Society, 1995 , vol. 117, # 36 p. 9139 - 9150
反应条件
in tetrahydrofuran 48 h; Heating;
参考文献
Chu, Lin; Fisher, Michael H.; Goulet, Mark T.; Wyvratt, Matthew J.
Tetrahedron Letters, 1997 , vol. 38, # 22 p. 3871 - 3874
反应条件
1: With hydrogen; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; [rhodium(I)(carbonyl)2(acetylacetonate)] in tetrahydrofuran T=70°C; P=15001.2 Torr; 68 h; 2: With sulfuric acid in tetrahydrofuran T=80°C; 2 h;
参考文献
Linnepe, Petra; Schmidt, Axel M.; Eilbracht, Peter
Organic and Biomolecular Chemistry, 2006 , vol. 4, # 2 p. 302 - 313
反应条件
1: With 1,4-diaza-bicyclo[2.2.2]octane in N,N-dimethyl-formamide 0.333333 h; 2: With palladium diacetate in N,N-dimethyl-formamide T=85°C;
参考文献
Hu, Chunmei; Qin, Hua; Cui, Yuxin; Jia, Yanxing
Tetrahedron, 2009 , vol. 65, # 45 p. 9075 - 9080
反应条件
1: 72 percent / methyltrioctylammonium chloride / dimethylformamide / 20 °C 2: 46 percent / XANTHPHOS; p-TsOH*H2O; H2 / Rh(acac)(CO)2 / tetrahydrofuran / 68 h / 60 - 100 °C / 15001.2 Torr View Scheme
参考文献
Schmidt, Axel M.; Eilbracht, Peter
Organic and Biomolecular Chemistry, 2005 , vol. 3, # 12 p. 2333 - 2343
反应条件
1: 85 percent / p-TsOH*H2O / ethanol / 80 °C 2: 46 percent / XANTHPHOS; p-TsOH*H2O; H2 / Rh(acac)(CO)2 / tetrahydrofuran / 68 h / 60 - 100 °C / 15001.2 Torr View Scheme
参考文献
Koehling, Petra; Schmidt, Axel M.; Eilbracht, Peter
Organic Letters, 2003 , vol. 5, # 18 p. 3213 - 3216
参考文献
Manske
Journal of the American Chemical Society, 1929 , vol. 51, p. 1203
Canadian Journal of Research, 1931 , vol. 4, p. 594
Chem. Zentralbl., 1931 , vol. 102, # II p. 2738
反应条件
triphenylphosphine; diethylazodicarboxylate Mitsunobu reaction;
参考文献
Ardeo, Ainhoa; Garcia, Eva; Arrasate, Sonia; Lete, Esther; Sotomayor, Nuria
Tetrahedron Letters, 2003 , vol. 44, # 46 p. 8445 - 8448
