2-甲基-[1,1-联苯]-2-甲腈合成路线 （共 18 条）
反应条件
potassium fluoride; 18-crown-6 ether; bis-phenanthrylimidazolium chloride; palladium diacetate in tetrahydrofuran T=50°C; Suzuki-Miyaura coupling; 12 h;
参考文献
Barder, Timothy E.
Journal of the American Chemical Society, 2006 , vol. 128, # 3 p. 898 - 904
反应条件
bis-triphenylphosphine-palladium(II) chloride; potassium carbonate in ethanol; water; toluene T=80°C; Suzuki-Miyaura cross coupling reaction; Inert atmosphere;
参考文献
Tnay, Ya Lin; Chen, Cheng; Chua, Yi Yuan; Zhang, Line; Chiba, Shunsuke
Organic Letters, 2012 , vol. 14, # 13 p. 3550 - 3553
反应条件
C21H18N8Ni2O(2+)*2F6P(1-) in tetrahydrofuran; 1-methyl-pyrrolidin-2-one T=20 - 80°C; Negishi coupling reaction;
参考文献
Xi, Zhenxing; Zhou, Yongbo; Chen, Wanzhi
Journal of Organic Chemistry, 2008 , vol. 73, # 21 p. 8497 - 8501
反应条件
potassium phosphate; (C5H5FeC5H3C(CH3)NC6H4CH3)PdCl(tricyclohexylphosphine); potassium acetate in 1,4-dioxane; water T=100°C; Suzuki coupling; 3 h; Inert atmosphere;
参考文献
Wang, Lianhui; Cui, Xiuling; Li, Jingya; Wu, Yusheng; Zhu, Zhiwu; Wu, Yangjie
European Journal of Organic Chemistry, 2012 , # 3 p. 595 - 603
反应条件
ethylene glycol dimethyl ether; Pd(1,3-bis(diphenylphosphino)-propane)Cl2 in tetrahydrofuran T=65°C; 2 h;
参考文献
Riguet, Eric; Alami, Mouad; Cahiez, Gerard
Journal of Organometallic Chemistry, 2001 , vol. 624, # 1-2 p. 376 - 379
反应条件
tetrabutylammomium bromide; N-ethyl-N,N-diisopropylamine; palladium diacetate in xylene T=130°C; 52 h;
参考文献
Hassan, Jwanro; Hathroubi, Chokri; Gozzi, Christel; Lemaire, Marc
Tetrahedron, 2001 , vol. 57, # 37 p. 7845 - 7855
反应条件
C35H31BrN4NiP in tetrahydrofuran T=25°C; 24 h; Schlenk techniqueInert atmosphere;
参考文献
Guo, Wang-Jun; Wang, Zhong-Xia
Journal of Organic Chemistry, 2013 , vol. 78, # 3 p. 1054 - 1061
反应条件
C16H16Cl2N2O4Pd2; tetrabutylammomium bromide; potassium carbonate in water 16 h; RefluxDarknessInert atmosphere;
参考文献
Alacid, Emilio; Najera, Carmen
Organic Letters, 2008 , vol. 10, # 21 p. 5011 - 5014
反应条件
potassium phosphate; (C5H5FeC5H3C(CH3)NC6H4CH3)PdCl(tricyclohexylphosphine); potassium acetate in 1,4-dioxane; water T=100°C; Suzuki coupling; 3 h; Inert atmosphere;
参考文献
Wang, Lianhui; Cui, Xiuling; Li, Jingya; Wu, Yusheng; Zhu, Zhiwu; Wu, Yangjie
European Journal of Organic Chemistry, 2012 , # 3 p. 595 - 603
反应条件
palladium diacetate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in toluene T=120°C; 24 h; Sealed tubeInert atmosphere;
参考文献
Zhou, Chao; Liu, Qingjiang; Li, Yaming; Zhang, Rong; Fu, Xinmei; Duan, Chunying
Journal of Organic Chemistry, 2012 , vol. 77, # 22 p. 10468 - 10472
