1: 67 percent / aq. HClO4 / 4 h / 20 °C 2: 1.) PhCO2H, DEAD, Ph3P, 2.) K2CO3, MeOH / 1.) THF, 0 deg C, 10 min, 2.) 20 deg C, 45 min 3: NEt3 / CH2Cl2 / 0.17 h / 0 °C 4: 1.) caesium acetate, 2.) K2CO3, MeOH / 1.) DMF, 40-50 deg C, 24 h, 2.) 20 deg C, 1 h 5: 100 percent / H2, AcOH / Pd black / 18 h View Scheme

1: 67 percent / aq. HClO4 / 4 h / 20 °C 2: 100 percent / H2, AcOH / Pd black / 18 h View Scheme